i-tert-butyl (2-chloropyridin-3-yl)carbamate CAS:209798-48-1

I-Tert-butyl (2-chloropyridin-3-yl)carbamate idlala indima ebalulekileyo njengomdibanisi ekuhlanganisweni kweekhompawundi ezintsonkothileyo, ezisebenzayo kunye nezicelo zamayeza ezinokubakho. Ukufakwa kwayo kwizakhelo zeemolekyuli kwenza abaphandi bakwazi ukuphonononga abaviwa abatsha bamayeza ajolise kwiindawo zonyango ezifana neengxaki zemithambo-luvo, izifo ezisulelayo, okanye i-oncology. Ubukho beqela le-chloropyridine bunika i-reactivity ethile kunye neempawu ze-pharmacophoric, nto leyo eyenza ukuba ibe luncedo kuphando lwekhemistri yamayeza. Ekufumaneni iziyobisi, le khompawundi ingasebenza njengendawo yokuqala yokuyila abaviwa abanokubakho bamayeza, isebenzisa iimpawu zayo zesakhiwo ukuguqula umsebenzi webhayoloji kunye neempawu ze-pharmacokinetic. Ukongeza, iqela le-tert-butyl libonelela ngomqobo we-steric, lichaphazela ukusebenzisana kwekhompawundi kunye neenjongo zebhayoloji kwaye linegalelo ekuhlolweni konyango olutsha. Ngaphezu koko, kwiindawo zemfundo nakwimizi-mveliso, abaphandi banokusebenzisa esi sakhiwo sokwakha ukulungiselela iilayibrari zezinto ezahlukeneyo eziphuma kuzo kwizifundo zobudlelwane besakhiwo-umsebenzi, okwenza kube lula ukuchongwa kweekhompawundi ze-lead ezineempembelelo zebhayoloji ezifunwayo. Indima yayo ekuhlanganisweni kweekhemikhali ifikelela kwimveliso yee-intermediates zamayeza kunye nophuhliso lweendlela ezintsha zokwenziwa, ibonisa ukusetyenziswa kwayo okubanzi kuzo zonke iinkalo zesayensi. Lilonke, i-tert-butyl (2-chloropyridin-3-yl)carbamate idlala indima ebalulekileyo ekufuneni ukufunyanwa kwamayeza amatsha kunye nophando lweekhemikhali, ibonelela ngeqonga lophuhliso lweemolekyuli ezahlukeneyo ezisebenzayo ngokwebhayoloji kunye nezinto ezidityanisiweyo zamayeza.