I-VALINOMYCIN CAS:2001-95-8 Ixabiso lomenzi

I-Valinomycin yi-antibiotiki yendalo ye-cyclic peptide eveliswa ikakhulu ziintlobo ezithile zebhaktheriya i-Streptomyces. Yenziwe ngumjikelo we-alternating D- kunye ne-L-amino acids, ene-central cyclic depsipeptide motif. I-Valinomycin yaziwa kakhulu ngokuthanda kwayo okuphezulu kwe-monovalent cations, ngakumbi i-potassium ions (K+).

Ngenxa yokukwazi kwayo ukubopha nokuthutha ii-ion ze-potassium ngokukhetha kwii-membrane zebhayoloji, i-valinomycin ifumene iindlela ezahlukeneyo zokusetyenziswa kuphando lwesayensi kunye ne-biotechnology. Isetyenziswa kakhulu njenge-ionophore kwii-electrodes ezikhetha ii-ion zokulinganisa ubuninzi be-potassium kwiisampuli zebhayoloji. Amandla akhethekileyo e-Valinomycin okuthutha ii-ion ze-potassium ngokukhetha akwenza kube luncedo kwizifundo zokuthuthwa kwee-ion kunye nokukwazi kwe-membrane kwiiseli.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Valinomycin isebenza kakhulu njenge-ionophore, oko kuthetha ukuba yenza kube lula ukuthuthwa kwee-ion ezithile kwiimembrane zeseli. Isiphumo sayo esiphawulekayo kukunamathela kwayo okukhulu kwii-ion ze-potassium (K+). I-Valinomycin yenza i-complex ene-K+ ions, nto leyo eyenza ukuba ikhetheke kakhulu ekuthuthweni kwayo.

Enye yezona ndlela ziphambili zokusetyenziswa kwe-valinomycin kukusebenzisa i-ionophore kwii-electrode ezikhetha i-ion ukulinganisa ubuninzi be-potassium kwiisampuli zebhayoloji. Ezi electrode zisebenzisa amandla e-valinomycin okubopha nokuthutha ii-ion ze-K+ ngokukhetha, nto leyo eyenza ukuba imilinganiselo ye-ion ye-potassium ichanekileyo kwaye ibe novakalelo.

Ubuchule beValinomycin bokuhambisa ii-ion ze-potassium buyenza ibaluleke kakhulu kuphando olunxulumene nokuthuthwa kwee-ion kunye nobuchule be-membrane kwiiseli. Isetyenziselwa ukufunda indima yeendlela ze-ion, amandla e-membrane, kunye ne-ion gradients kwiinkqubo ezahlukeneyo zebhayoloji.

Ngaphezu koko, i-valinomycin iphandwe ngezicelo zayo zonyango. Ibonakalise iziphumo ezithembisayo njengearhente yokulwa nomhlaza kwiintlobo ezithile zomhlaza. I-Valinomycin ibangela i-apoptosis (ukufa kweeseli) kwiiseli zomhlaza ngokuphazamisa amandla azo e-mitochondrial membrane.

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C54H90N6O18
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	2001-95-8
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.