IVithamini B13 (iOrotic Acid) I-CAS: 65-86-1 Umthengisi woMvelisi Umfanekiso oPhambili

IVithamin B13 (iOrotic Acid) I-CAS: 65-86-1 Umthengisi woMvelisi

I-Orotic acid (ekwaziwa ngokuba yi-pyrimidinecarboxylic acid) yi-heterocyclic acid; ikwabizwa ngokuba yi. Ngokwembali yayikholelwa ukuba iyinxalenye ye-vitamin B complex kwaye yayibizwa ngokuba yi-vitamin B13, kodwa ngoku yaziwa ukuba ayisiyo-vitamin. Yaziwa kakhulu njengesandulela kwi-biosynthesis ye-pyrimidines; kwizilwanyana ezincancisayo ikhutshwa kwi-mitochondrial dihydroorotate dehydrogenase (DHODH) ukuze iguqulwe ibe yi-UMP yi-cytoplasmic UMP synthase enzyme. I-OA ikwayinxalenye eqhelekileyo yokutya, ifumaneka kubisi nakwiimveliso zobisi, kwaye iguqulwa ibe yi-uridine ukuze isetyenziswe kwindlela yokusindisa i-pyrimidine ikakhulu kwisibindi, izintso kunye nee-erythrocytes.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Orotic acid yi-intermediate in de novo pyrimidine biosynthesis enokusetyenziswa ukufunda ubunyani kunye ne-kinetics ye-orotate phosphoribosyltransferase (OPRT) ekhuthaza ukudluliselwa kwe-phosphoribosyl eguqukayo ukusuka kwi-5?-phospho-α-d-ribose 1?-diphosphate (PRPP) ukuya kwi-orotic acid (OA), okwenza i-pyrophosphate kunye ne-orotidine 5?-monophosphate (OMP). Isetyenziswa njengesixhobo sokuqala kwimveliso ye-uridine 5?-monophosphate (UMP) yezorhwebo yiintsholongwane ezifana neCorynebacterium ammoniagenes (ATCC 6872) okanye iSaccharomyces cerevisiae. Ingasetyenziselwa ukufunda indlela yokubonisa iseli exhomekeke kwi-AMPK/SREBP-1 kunye neendlela zokulawula ukubhalwa kwemibhalo ezibangela i-hepatic lipogenesis.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C5H4N2O4
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	65-86-1
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.