I-Z-Arg-OH CAS:1234-35-1

I-Z-Arg-OH isebenza njengecandelo elibalulekileyo ekuqulunqweni kwe-peptide yesigaba esiqinileyo, idlala indima ebalulekileyo ekwakheni iipeptides ezinolandelelwano olucwangcisiweyo. Ngokususa ngokukhetha iqela le-Z phantsi kweemeko ezithambileyo, iqela le-guanidino eliveziweyo livumela ukwandiswa okungakumbi kwekhonkco le-peptide kwinkxaso eqinileyo. Ukongeza, i-Z-Arg-OH inegalelo ekudalweni kwamayeza asekelwe kwi-peptide, ngakumbi kuphuhliso lwamayeza ajolise kwiindlela ezithile zebhayoloji kunye nokusebenzisana. Ngaphezu koko, le khompawundi ifumana ukusetyenziswa okubanzi ekufundeni ukusebenzisana kweproteni-protein, umsebenzi we-enzymatic, kunye neziganeko zokubopha i-receptor-ligand. Ukusetyenziswa kwayo kufikelela kuphuhliso lweemolekyuli ezintsha ze-organic ezinemisebenzi enokubakho yebhayoloji, okwenza ukuba ibe sisixhobo esibalulekileyo kuphando lweekhemikhali, lwe-biochemical, kunye nolwe-pharmaceutical. Abaphandi basebenzisa i-Z-Arg-OH ukwenza iipeptides ezenziwe ngokwezifiso kwiintlobo ngeentlobo zezicelo, kubandakanya uphuhliso lwamayeza, i-molecular imaging, kunye nezifundo zebhayoloji yesakhiwo. Ukuqukumbela, ukuguquguquka kunye nokuhambelana kwe-Z-Arg-OH neendlela ezahlukeneyo zokwenziwa kwenza ukuba ibe sisixhobo esibalulekileyo kwizazinzulu kunye nabaphandi abagxile kwi-peptide kunye ne-organic chemistry. Ibanika amandla okutyhila izakhiwo zeemolekyuli ngobuchule kwaye baphuhlise iikhompawundi ezintsha zokusetyenziswa ezahlukeneyo kwicandelo lonyango, ukuxilongwa, kunye nophando olusisiseko.