I-Z-MeLeu-OH CAS:33099-08-0

Ukukhuthaza ukukhula: I-L-Arginine yaziwa ngokukhuthaza ukukhululwa kwehomoni yokukhula kwizilwanyana, nto leyo enokubangela iingxaki

Abaphandi basebenzisa rhoqo i-Z-MeLeu-OH kwi-peptide chemistry ukuze baguqule ii-peptides kwindawo ethile. Ngokufaka i-Z-MeLeu-OH kulandelelwano lwee-peptide, izazinzulu zinokungenisa i-methylated leucine residue, nto leyo evumela ukuba kufundwe imiphumo ye-methylation kwisakhiwo se-peptide, uzinzo, kunye nokusebenzisana nezinye iimolekyuli. Ukongeza, i-Z-MeLeu-OH ingasetyenziswa njengebhloko yokwakha ukuhlanganiswa kwee-peptides eziguquliweyo ezinemisebenzi ethile okanye iipropati, ukwandisa ububanzi bophando olusekelwe kwi-peptide kunye nokusetyenziswa ekufumaneni amayeza, ii-proteomics, kunye ne-chemical biology. Ukuhambelana kwayo nemigaqo eqhelekileyo yokwenziwa kwe-peptide kunye namaqhinga okudibanisa i-bio kwenza i-Z-MeLeu-OH ibe yi-reagent exabisekileyo kubaphandi abafuna ukulawula nokufunda izakhiwo ze-peptide kunye nemisebenzi ngokuchanekileyo.

Inika imbeko ekukhuleni nasekuphuhlisweni okuphucukileyo. Ikhuthaza ukwenziwa kweproteni, ebalulekileyo ekukhuleni kwezihlunu, kwaye inokuphucula ukwanda kobunzima bomzimba kwizilwanyana.

Ukuveliswa kwe-nitric oxide: I-L-Arginine sisandulela sokwenziwa kwe-nitric oxide (NO) emzimbeni. I-nitric oxide ibandakanyeka kwiinkqubo ezahlukeneyo ze-physiological, kubandakanya ukwanda kwemithambo yegazi, ukusebenza komzimba, kunye nokuhanjiswa kwemiqondiso yeeseli. Ukongeza i-L-Arginine ekutyeni kwezilwanyana kunokunyusa ukuveliswa kwe-NO, okukhokelela ekuphuculeni ukuhamba kwegazi, impendulo yomzimba, kunye nokufunxwa kwezondlo.

Umsebenzi womzimba: I-L-Arginine idlala indima ebalulekileyo ekuxhaseni inkqubo yomzimba yokuzikhusela. Ibandakanyeka ekuvelisweni kweeseli zomzimba zokuzikhusela, ezifana nee-T-cells kunye nee-macrophages, kunye nee-antibodies. Ngokubonelela ngobonelelo olwaneleyo lwe-L-Arginine ekutyeni kwezilwanyana, umsebenzi womzimba wokuzikhusela unokuphuculwa, nto leyo ekhokelela ekuphuculeni ukuxhathisa izifo kunye nempilo iyonke.

Ukusebenza kokuzala: I-L-Arginine ibalulekile kwiinkqubo zokuzala kwizilwanyana. Ibandakanyeka kwimveliso yesidoda kunye nokuhambahamba kwamadoda kwaye inokuphucula ukuzala. Kwabasetyhini, i-L-Arginine ixhasa uphuhliso kunye nomsebenzi wesibeleko kunye ne-placenta, iphucula ukusebenza kokuzala kunye nokwandisa ubungakanani beentsana.

Ulawulo loxinzelelo: I-L-Arginine ibonakalisiwe inefuthe elihle kwindlela izilwanyana ezisabela ngayo kuxinzelelo. Inganciphisa amanqanaba e-cortisol abangelwa luxinzelelo kwaye ikhuthaze imeko yokuphumla. Ngokufaka i-L-Arginine ekutyeni kwezilwanyana, ukunyamezela uxinzelelo kunye nokuphila kakuhle kunokuphuculwa.