1,1,3,3-TetramethylGuanidine CAS:80-70-6

I-1,1,3,3-Tetramethylguanidine (TMG) inezicelo ezahlukeneyo kwiindawo ezininzi, ngakumbi kwi-organic synthesis nakwiinkqubo zoshishino. Njengesiseko esomeleleyo, isetyenziselwa ii-deprotonation reactions, kubandakanya i-deprotonation yee-asidi, ivumela utshintsho olwahlukeneyo lwe-synthetic olufana ne-condensations, i-eliminations, kunye ne-nucleophilic substitutions. I-TMG idlala indima ebalulekileyo ekulungiseleleni ii-pharmaceutical intermediates, ii-agrochemicals, kunye neekhemikhali ezikhethekileyo. Ubunzima bayo obuphezulu buyenza ifaneleke kakuhle ekukhuthazeni ii-carbon-carbon bond-forming reactions ezahlukeneyo, kubandakanya i-synthesis yee-polymers, ii-resins, kunye nezinto ezisebenzayo. Ngaphezu koko, i-TMG isetyenziswa kwicandelo le-catalysis, ngakumbi kwiinkqubo ze-metal-catalyzed reactions kunye ne-polymerization, enegalelo kwimveliso yeekhemikhali ezikhethekileyo kunye nezinto eziphambili. Ukongeza kwindima yayo kwi-chemical synthesis, i-TMG isetyenziswa njenge-catalyst ekuvelisweni kweekhemikhali ezintle nakwimveliso yee-pharmaceutical compounds. Amandla ayo okwenza lula i-asymmetric synthesis abalulekile ekudaleni ii-chiral compounds ezibalulekileyo ekufumaneni nasekuphuhlisweni kwamayeza. Ngaphezu koko, ukusetyenziswa kwe-TMG kufikelela ekulungiseleleni izinyibilikisi ezikhethekileyo kunye nee-reagents ezisetyenziswa kwiinkqubo ezahlukeneyo zoshishino. Ngokubanzi, uluhlu olubanzi lokusetyenziswa kwe-1,1,3,3-Tetramethylguanidine lugxininisa ukubaluleka kwayo ekuphuculeni zombini ukusetyenziswa kweekhemikhali kunye nokusetyenziswa kwezoshishino.