2′-(4-METHYLUMBELLIFERIYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM ITYUWA CAS:76204-02-9 Umfanekiso obonisiweyo

2′-(4-METHYLUMBELLIFERIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM ITYUWA CAS:76204-02-9

Ityuwa yesodium ye-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid yikhemikhali esetyenziswa kakhulu kwiimvavanyo zokuxilonga nophando. Yi-derivative ye-sialic acid ebhalwe fluorescent, uhlobo lwemolekyuli ye-carbohydrate efumaneka kumphezulu weeseli.

Le khompawundi isetyenziswa njengesiseko see-enzymes ezibizwa ngokuba yi-neuraminidases, ezisebenza ukususa iintsalela ze-sialic acid kwi-glycoproteins kunye ne-glycolipids. Xa ezi enzymes zisebenza kwi-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid sodium salt, ikhupha imveliso ekhanyayo eyaziwa ngokuba yi-4-methylumbelliferone.

I-fluorescence eveliswa yile compound ingalinganiswa kwaye ilinganiswe, inike ulwazi malunga nomsebenzi wee-enzymes ze-neuraminidase. Oku kuluncedo ngakumbi ekufundeni izifo ezahlukeneyo kunye neemeko ezinxulumene ne-aberrant sialic acid metabolism.

Le khompawundi ikwasetyenziselwa iinjongo zokuxilonga, njengokufumanisa usulelo lwentsholongwane olubandakanya umsebenzi we-neuraminidase. Kolu vavanyo, le khompawundi isetyenziselwa ukuchonga ubukho beentlobo ezithile zentsholongwane okanye ukuvavanya ukusebenza kakuhle kwe-neuraminidase inhibitors kunyango lwe-antiviral.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

Uvavanyo lomsebenzi weNeuraminidase: Le khompawundi isetyenziswa rhoqo ukulinganisa umsebenzi wee-enzymes ze-neuraminidase kwiisampuli zebhayoloji. Ngokujonga ukukhanya okuveliswayo, abaphandi banokumisela inqanaba lomsebenzi we-neuraminidase, nto leyo enokunceda ekufundeni izifo ezahlukeneyo kunye neemeko.

Ukufunyanwa Kosulelo Lweentsholongwane: Iintsholongwane ezininzi, kuquka umkhuhlane, zibandakanya umsebenzi we-neuraminidase. Le khompawundi ingasetyenziselwa ukufumanisa nokulinganisa ubukho beentlobo ezithile zentsholongwane ngokulinganisa umsebenzi we-fluorescent. Iluncedo ngakumbi ekuvavanyeni ukusebenza kakuhle kwe-neuraminidase inhibitors kunyango lwe-antiviral.

Uhlalutyo lweGlycosylation: I-asidi yeSialic yinxalenye ebalulekileyo yee-glycoproteins kunye nee-glycolipids. Ngokudibanisa ityuwa yesodium ye-2'-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid kwiimvavanyo, abaphandi banokufumana ulwazi malunga nemetabolism ye-sialic acid, iipateni ze-glycosylation, kunye neenkqubo ezinxulumene noko ze-physiological.

Ukufunyanwa Kwamayeza: Ii-Neuraminidase inhibitors luhlobo lwamayeza asetyenziswa kunyango lwezifo ezibangelwa yintsholongwane. Le khompawundi ingasetyenziswa kwizifundo zokufunyanwa kwamayeza, inceda abaphandi ukuba babone kwaye bavavanye ii-inhibitors ezinokubakho zomsebenzi we-neuraminidase.

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C21H26NNaO11
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	76204-02-9
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.