(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid I-CAS:132622-69-6

I-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid isebenza njengesiseko esibalulekileyo sokwakha iipeptides kunye neepeptidomimetics ezinemisebenzi eyahlukeneyo ye-bioactivity kunye nobuchule bonyango. Ukufakwa kwayo kwiitsheyini zepeptide kwenza kube lula ukudalwa kweekhompawundi ezifanelekileyo kwi-pharmacologically, kubandakanya ii-peptide hormones, ii-enzyme inhibitors, kunye namayeza anokubakho. Ukongeza, le khompawundi isetyenziswa ekulungiseleleni amayeza asekelwe kwi-peptide ophando, ukuxilongwa, kunye neenjongo zonyango, inegalelo kuphuhliso lonyango olutsha kwiimeko ezahlukeneyo zonyango. Ngaphezu koko, i-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid isetyenziswa kakhulu kwi-solid-phase peptide synthesis (SPPS), okwenza kube lula ukuhlanganiswa okusebenzayo nokulawulwayo kwe-complex peptide sequences. Ukuhambelana kwayo neendlela ze-SPPS kuvumela ukuveliswa kweepeptides ezenziwe ngokwezifiso kunye neelayibrari ze-peptide ezisetyenziswa kwizifundo zebhayoloji, ukuhlolwa kwamayeza, kunye nophando lwe-biochemical, nto leyo egxininisa indima yayo ebalulekileyo ekuphuculeni ubuchwepheshe obusekelwe kwi-peptide. Ngaphezu koko, le khompawundi isetyenziswa kwiilabhoratri zemfundo kunye nezoshishino ukuphanda i-reacction ye-peptide, ubudlelwane bolwakhiwo-umsebenzi, kunye namaqhinga okuguqula i-peptide, exhasa ukuqhubela phambili kwi-peptide chemistry kunye nokufunyanwa kwamayeza. Ngokubanzi, ukusetyenziswa okune-multifaceted kwe-(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid kugxininisa indima yayo ebalulekileyo kuphando lwe-peptide, ukwenziwa kwamayeza, kunye nophuhliso lwezonyango ezisekelwe kwi-peptide, okuqhuba inkqubela phambili kwi-biotechnology kunye ne-medical chemistry.