4,4′-Diaminodiphenyl sulfone (Dapsone) CAS:80-08-0

I-Dapsone liyeza elisetyenziswa ngeendlela ezahlukeneyo ekulawuleni iimeko ezahlukeneyo zesikhumba ngenxa yeempawu zalo zokulwa namagciwane kunye nokulwa nokuvuvukala. Lidla ngokumiselwa unyango lweqhenqa (isifo sikaHansen), isifo esosulelayo esingapheliyo esibangelwa yiMycobacterium leprae esichaphazela ulusu kunye nemithambo-luvo. I-Dapsone ikwasebenza ekunyangeni i-dermatitis herpetiformis, isifo esingapheliyo solusu esibangela amaqhubu emzimbeni esinxulunyaniswa nesifo se-celiac. Ukongeza kwezi mpawu ziphambili, i-Dapsone ingasetyenziswa ngaphandle kweleyibhile ukulawula ezinye iimeko zesikhumba ezifana ne-acne vulgaris, i-bullous pemphigoid, kunye ne-cutaneous lupus erythematosus. Eli yeza lifumaneka kwifom yethebhulethi yomlomo kunye namalungiselelo angaphandle, okuvumela ababoneleli bezempilo ukuba balungelelanise iindlela zonyango ngokweemfuno zesigulana ngasinye kunye nobunzima besifo. Izigulana ezisebenzisa unyango lwe-Dapsone kufuneka zilandele imiyalelo yomboneleli wezempilo ngononophelo malunga nokuphindaphinda kwedosi, ubude bonyango, kunye neziphumo ebezingalindelekanga. Ukujonga rhoqo inani legazi kunye novavanyo lomsebenzi wesibindi kunokufuneka ukuqinisekisa ukusetyenziswa kwamayeza okukhuselekileyo kunye nokubonwa kwangoko kweziphumo ezibi. Kubalulekile ukuba izigulana zixelele umboneleli wazo wezempilo ngazo naziphi na iingxaki okanye utshintsho kwimeko yazo ngexesha lonyango lweDapsone ukuze kuphuculwe iziphumo zonyango kwaye kuncitshiswe umngcipheko weengxaki. Ngokulandela inkqubo emiselweyo kunye nokugcina unxibelelwano oluvulekileyo neqela labo lezempilo, izigulana zinokuzuza kwimiphumo yonyango lweDapsone ekulawuleni iimeko ezahlukeneyo zesikhumba ngokufanelekileyo.