I-Acetylthiocholine iodide CAS:1866-15-5

Ukulinganiswa komsebenzi we-acetylcholinesterase (AChE): I-Acetylthiocholine iodide isetyenziswa kakhulu njengesiseko kwiimvavanyo ze-enzyme ukulinganisa umsebenzi we-AChE. I-AChE yi-enzyme edibanisa i-acetylcholine ne-hydrolyzes, kwaye ngokulinganisa umsebenzi wayo, abaphandi banokuvavanya umsebenzi we-cholinergic kunye nemiphumo yamayeza, iityhefu, okanye izifo kwi-AChE.

Isixhobo sokuxilonga kwiingxaki ze-neurodegenerative: Ukungasebenzi kakuhle kwe-AChE kubonakala kwizifo ezininzi ze-neurodegenerative, kuquka nesifo se-Alzheimer. Ukulinganiswa komsebenzi we-AChE kusetyenziswa i-acetylthiocholine iodide kunokunceda ekuxilongeni nasekujongeni ezo ngxaki.

Izifundo zeToxicology: I-Acetylthiocholine iodide ikwasetyenziswa kwizifundo zeToxicology ukuvavanya imiphumo yeekhemikhali okanye iityhefu kumsebenzi we-AChE. Iikhemikhali ezithile, ezifana ne-organophosphate kunye ne-carbamate insecticides, zinokuthintela umsebenzi we-AChE, nto leyo ekhokelela kwimiphumo enobungozi. I-Acetylthiocholine iodide inokubonelela ngengqiqo malunga nobutyhefu kunye neendlela zokusebenza kwezi zinto.

Ukuhlolwa kwee-AChE inhibitors: I-Acetylthiocholine iodide isetyenziswa ekufumaneni nasekuphuhliseni amayeza ukuchonga nokuchonga ii-AChE inhibitors ezinokubakho. Ii-inhibitors ze-AChE zinokuba luncedo ekunyangeni iimeko ezahlukeneyo, kuquka nesifo se-Alzheimer.

Uphuhliso lwee-biosensors: I-Acetylthiocholine iodide, kunye ne-AChE, isetyenziswa ekuphuhlisweni kwee-biosensors zokufumanisa i-acetylcholine. Ezi biosensors zifumana ukusetyenziswa kwiindawo ezifana nokubeka esweni okusingqongileyo kunye nokuxilongwa kweklinikhi.