I-Clascoterone CAS:19608-29-8 Umthengisi woMvelisi

I-Clascoterone sisithinteli se-androgen receptor esiphuhliswa njengekhrimu kunye nesisombululo se-topical yiCassiopea (inkampani yeCosmo Pharmaceuticals) yokunyanga iingxaki zesikhumba ezixhomekeke kwi-androgen, kubandakanya i-androgenetic alopecia kunye ne-acne vulgaris. Nangona indlela echanekileyo yokusebenza kwe-clascoterone kunyango lwe-acne vulgaris ingaziwayo, eli yeza kukholelwa ukuba likhuphisana ne-androgen dihydrotestosterone yokubopha kwi-androgen receptors kwi-sebaceous gland kunye ne-hair follicles ukunciphisa imiqondiso efunekayo kwi-acne pathogenesis.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Clascoterone iphuhliswa njengekhrimu yokuthambisa ekwindawo engaphandle yiCassiopea yeengxaki zesikhumba ezixhomekeke kwi-androgen. I-Clascoterone (i-cortexolone 17α-propionate, CB-03-01) yinto entsha echasene nee-receptors ze-androgen. Ibopha kwii-receptors ze-androgen ngokunamathela okuphezulu. Ngokukhuphisana nee-androgens ukuze zibophane nee-receptors ze-androgen, i-clascoterone isebenza ngokuthintela ii-cascade ze-androgen receptor signalling ezikhuthaza i-acne pathogenesis, njengokwanda kwe-sebaceous gland, ukuveliswa kwe-sebum egqithisileyo, kunye neendlela zokudumba. Ngo-Agasti 2020, i-FDA yavuma i-clascoterone yonyango lokuqala lwe-acne (acne vulgaris) kwizigulane ezingamadoda nabasetyhini ezineminyaka eli-12 nangaphezulu. I-Clascoterone ikwaphandwa njengonyango olutsha lwe-androgenetic alopecia.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C24H34O5
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	19608-29-8
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.