I-Clozapine N-oxide CAS: 34233-69-7 Ixabiso lomenzi

I-Clozapine N-oxide yi-metabolite ye-clozapine yeyeza le-antipsychotic. Ifumene ingqalelo kuphando ngenxa yokusetyenziswa kwayo okunokwenzeka kwi-optogenetics, indlela esebenzisa ukukhanya ukulawula iiseli kwizicubu eziphilayo, ngokuqhelekileyo ii-neurons. Kwizifundo ze-optogenetic, i-clozapine N-oxide ingasetyenziselwa ukulawula umsebenzi wee-receptors zoyilo ezisebenza kuphela ngamayeza oyilo (ii-DREADD), ezizii-molecular switches ezenziwe ngobunjineli eziphendula kwi-clozapine N-oxide. Olu setyenziso luvumela abaphandi ukuba balawule ii-neural circuits ezithile kwaye bafunde umsebenzi wazo. Ukongeza, i-clozapine N-oxide ikwafundwe ngemiphumo yayo enokubakho yonyango kwizifo zengqondo kunye neze-neurological.