I-Duloxetine HCL CAS:136434-34-9 uMboneleli woMvelisi

I-Duloxetine HCL luhlobo lwetyuwa lweyeza lokuthomalalisa i-duloxetine.Yaphuhliswa ngempumelelo nguEli Lilly Inkampani.Impembelelo yayo ye-pharmacological iyafana ne-duloxetine.I-Duloxetine hydrochloride luhlobo olutsha olukhethiweyo lwe-dual inhibitor ye-5 hydroxy trptamine (5-HT) kunye ne-norepinephrine reuptake, kwaye ngaloo ndlela ibe nefuthe elichasayo, ngelixa libuye libe nefuthe lokuthintela kwintlungu ephakathi.Uphawu lwayo lwe-pharmacological lukwazi ukuthintela ukuphindaphinda kwe-neuronal pre-synaptic membrane kwi-5-hydroxy trptamine kunye ne-norepinephrine kodwa endaweni yoko ibe nefuthe eliphantsi lokuthintela ekuthathweni kwakhona kwe-dopamine.I-Duloxetine hydrochloride iboniswa ukudakumba kwaye iyasebenza ekunyangeni ukudakumba okungapheliyo kunye nokungabikho kwesiphelo kunye nokuziva iintlungu ezinxulumene nokudakumba.Inomthamo wonyango we-60mg/d ~ 120mg/d ngokhuseleko olulungileyo kunye neempendulo ezingalunganga ezimbalwa kunye neziphumo ezibi eziqhelekileyo ezifana nesicaphucaphu, umlomo owomileyo, ukuqunjelwa, ukungakuthandi ukutya, ukudinwa, ukozela, kunye nokunyuka kokubila.Olunye uphawu ziintlungu ezibangelwa sisifo seswekile.