I-Egtazic acid CAS: 67-42-5 Ixabiso lomvelisi

I-Ethylenebis(oxyethylenenitrilo)tetraacetic acid (EGTA) yi-agent ye-chelating eqhele ukusetyenziswa kuphando lwebhayoloji kunye neekhemikhali.Yikhompawundi yokwenziwa ephuma kwi-ethylenediamine kunye ne-ethylene glycol.I-EGTA inobudlelwane obuphezulu bee-ion zensimbi ezidityanisiweyo, ngakumbi i-calcium, kwaye isetyenziswa ngokubanzi ukutshekisha kunye nokuhlutha ezi ion kwizicelo ezahlukeneyo ezifana nenkcubeko yeeseli, uvavanyo lwe-enzyme, kunye nobuchule bebhayoloji yemolekyuli.Ngokuzibophelela kwi-calcium kunye nezinye i-ion zetsimbi, i-EGTA inceda ukulawula ukugxininiswa kwabo, ngaloo ndlela ibe nefuthe kwiinkqubo ezahlukeneyo ze-biochemical.

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I-Calcium chelation: I-EGTA inobudlelwane obuphezulu be-calcium ions kwaye inokubophelela ngokufanelekileyo, ukunciphisa ukuxinwa kwe-calcium yamahhala kwisisombululo.Le propati yenza i-EGTA ibe luncedo ekufundeni indima ye-calcium kwiinkqubo ezahlukeneyo zebhayoloji.

I-Calcium buffer: I-EGTA isoloko isetyenziselwa ukwenza i-calcium-free okanye i-low calcium buffers ukwenzela imifuniselo.Nge-chelating calcium, i-EGTA inceda ekugcineni i-concentration efunekayo ye-calcium ion kwisisombululo, ivumela abaphandi ukuba balawule ukuphendula okuxhomekeke kwi-calcium.

Ukumodareyitha komsebenzi we-Enzyme: Ii-enzymes ezininzi zifuna ii-ion zetsimbi ezithile, kuquka i-calcium, kumsebenzi wazo.I-EGTA ingasetyenziselwa ukulungelelanisa umsebenzi we-enzyme ngokutshisa kunye nokususa ezi ion zetsimbi ezifunekayo kumxube wokusabela.

Ukuchithwa kweeseli: I-EGTA iluncedo kwi-cell dissociation kunye neenkqubo ze-tissue disaggregation.Inceda ukuphula i-cell-cell kunye ne-cell-extracellular matrix interactions by chelating i-calcium-dependent adhesion molecules, ekhokelela kwi-detachment of cells.

Izifundo zesalathiso seCalcium: Ukukwazi kwe-EGTA chelate calcium ion kunenzuzo kwizifundo zesikhombisi se-calcium.Ngokulawula i-concentration ye-calcium ions yamahhala kunye ne-EGTA, abaphandi banokuhlola ngokuchanekileyo indima ye-calcium kwi-intracellular signaling kunye nezinye iinkqubo ze-physiological.

Ubuchwephesha bebhayoloji yemolekyuli: I-EGTA isetyenziswa kwiindlela ezahlukeneyo zebhayoloji yemolekyuli njenge-DNA kunye ne-RNA yokutsalwa, ukucocwa kweeprotheyini, kunye novavanyo lwe-enzyme.Inceda ukuzinzisa i-nucleic acids kunye neeprotheni ngokuthintela ukuthotywa kwe-metal-ion mediated.

Inkcubeko yeseli: I-EGTA isetyenziswa ngokuqhelekileyo kwinkcubeko yeseli ukugcina amanqanaba aphantsi e-calcium ukufunda iinkqubo zeselula ezixhomekeke kwi-calcium ngokuchanekileyo.Iququzelela ukususwa kwe-calcium kwimithombo yeendaba yokukhula, ivumela abaphandi ukuba baphande indima ye-calcium kwi-biology yeseli.

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Iinkcukacha ezongezelelweyo:

Ukuqamba	I-C14H24N2O10
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	67-42-5
Ukupakisha	Incinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.