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I-Cytidine-5′-monophosphate (CMP), i-asidi yasimahla i-CAS:63-37-6
I-Cytidine 5'-monophosphate (CMP) yi-nucleotide esebenza njengebhloko yokwakha i-RNA synthesis kunye nokuguqulwa kwayo. Yinto ebalulekileyo ekwakhiweni kwee-molecules ze-RNA kwaye ibandakanyeka kwiinkqubo ezifana ne-mRNA capping kunye ne-nucleotide metabolism. I-CMP ikwasetyenziswa kuphando lwe-biochemical kunye ne-molecular biology kwizicelo ezifana ne-in vitro transcription kunye ne-nucleic acid labeling. Indima yayo kwi-RNA metabolism kunye nokusetyenziswa kwayo kwiindlela ezahlukeneyo zovavanyo kwenza ukuba ibe sisixhobo esibalulekileyo ekuqondeni ulwakhiwo kunye nomsebenzi wee-molecules ze-RNA.
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I-IBMX, i-3-isobutyl-1-methylxanthine CAS:28822-58-4
I-3-isobutyl-1-methylxanthine, ekwaziwa ngokuba yi-IBMX, yi-methylxanthine derivative esetyenziswa kakhulu kuphando lwesayensi njengesithinteli esingangqalanga se-cyclic nucleotide phosphodiesterases. Iyaziwa ngokunyusa amanqanaba angaphakathi kweseli e-cyclic AMP (cAMP) kunye ne-cyclic GMP (cGMP) ngokuthintela ukuqhekeka kwazo, nto leyo enokuthi iguqule iindlela ezahlukeneyo zokubonisana kweeseli.
Ukongeza kwizicelo zayo zophando, i-IBMX isetyenzisiwe kwezinye iindawo zonyango ngenxa yemiphumo yayo ye-bronchodilator kunye ne-vasodilator. Nangona kunjalo, ukusetyenziswa kwayo kumayeza abantu kulinganiselwe.
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I-4-Nitrophenyl phosphate disodium salt hexahydrate CAS:4264-83-9
I-4-Nitrophenyl phosphate disodium salt hexahydrate yikhemikhali esetyenziswa rhoqo kuphando lwe-biochemical kunye ne-pharmaceutical. Yindlela yetyuwa ye-4-nitrophenyl phosphate, equlethe ii-ion ezimbini ze-sodium kunye neemolekyuli zamanzi ezintandathu. Le khemikhali isetyenziswa kakhulu njengesiseko sovavanyo lwe-phosphatase nakwisifundo se-enzyme kinetics.
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I-5′-Deoxy-5-fluorocytidine CAS:66335-38-4
I-5′-Deoxy-5-fluorocytidine yi-analog ye-nucleoside eyenziweyo ephandwayo ngenxa yomsebenzi wayo onokubakho wokulwa neentsholongwane, ingakumbi ngokuchasene neentsholongwane ze-RNA ezifana ne-hepatitis C virus (HCV) kunye nee-flavivirus. Isebenza ngokuphazamisa ukuphindaphinda kwezinto zemfuza zentsholongwane, ekugqibeleni ithintela amandla entsholongwane okwanda nokusasazeka emzimbeni.
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I-Cytidine-5′-triphosphate (CTP), ityuwa ye-disodium I-CAS:652154-13-7
Ityuwa ye-disodium iCytidine-5′-triphosphate (CTP), yi-nucleoside triphosphate esebenza njengebhloko yokwakha i-RNA. Idlala indima ebalulekileyo kwi-metabolism yeseli kwaye ibalulekile ekudlulisweni kolwazi lwe-genetic ukusuka kwi-DNA ukuya kwi-RNA ngexesha lokubhalwa kwe-transcription. I-CTP isetyenziswa kakhulu kuphando lwe-molecular biology, ngakumbi kwizifundo ezinxulumene nokuhlanganiswa kwe-RNA, ukuphazamiseka kwe-RNA, kunye nezinye iinkqubo ezinxulumene ne-RNA. Ukongeza, isetyenziswa kwiimpendulo ze-enzyme, izifundo ze-nucleotide metabolism, kunye nesiseko see-biochemical assays ezahlukeneyo. Kwishishini lezemithi, i-CTP inokuba nezicelo ezinokubakho kuphuhliso lwamayeza okulwa neentsholongwane kunye nomhlaza.
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ITP, inosine 5′-triphosphate trisodium salt CAS:35908-31-7
Ityuwa ye-Inosine-5′-triphosphate trisodium, edla ngokufinyezwa njenge-ITP-Na3, luhlobo lwe-inosine ye-triphosphate, i-nucleoside edlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zebhayoloji. Le khompawundi yifom yetyuwa, eyenza ukuba inyibilike emanzini kwaye ifanele ukusetyenziswa kwiimvavanyo ze-biochemical kunye ne-enzymatic, kunye nophando lwebhayoloji ye-molecular. Ityuwa ye-Inosine-5′-triphosphate trisodium isetyenziselwa ukufunda iimpendulo ze-enzymatic, i-nucleotide interconversion, kunye ne-substrate yee-enzymes ezithile. Ukusetyenziswa kwayo kukwafikelela kwizifundo ze-nucleotide analog kwaye njengenxalenye ekulungiseleleni imixube ye-nucleotide esetyenziswa kwiindlela zebhayoloji ye-molecular.
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I-5-Bromouracil CAS: 51-20-7 Ixabiso lomenzi
I-5-Bromouracil yi-analog yokwenziwa ye-uracil, eyinxalenye ye-RNA. I-5-Bromouracil inokufakwa kwi-nucleic acids kwaye inokubangela utshintsho ngokungasebenzi kakuhle ne-guanine ngexesha lokuphindaphindwa kwe-DNA. Isetyenziswa njenge-mutagen kuphando lwe-genetic ukufunda amazinga otshintsho kunye neendlela.
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I-5-Fluoro-2′-deoxyuridine CAS:50-91-9
I-5-Fluoro-2′-deoxyuridine yi-analog ye-nucleoside yokwenziwa ethintela ukwenziwa kwe-DNA. Ifundwe ngenxa yeempawu zayo ezinokubakho zokulwa neentsholongwane kunye nokulwa nomhlaza. Ukongeza, isetyenziswa njengesixhobo sophando kwi-molecular biology kunye ne-biochemistry.
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Ityuwa ye-disodium yeCytidine-5′-triphosphate CAS:36051-68-0
Ityuwa ye-disodium yeCytidine-5′-triphosphate (CTP-Na2) yi-nucleoside triphosphate esebenza njengebhloko yokwakha kwi-RNA. Idlala indima ebalulekileyo kwi-metabolism yeseli, isebenza njengesiseko se-RNA polymerases kwi-transcription kwaye njengomthombo wamandla kwiimpendulo ezahlukeneyo ze-enzyme. I-CTP-Na2 idla ngokusetyenziswa kuphando lwe-biochemical kunye ne-molecular biology njengenxalenye kwiimpendulo ezibandakanya ukwenziwa kwe-RNA, ukuguqulwa, kunye nokulawulwa kwayo. Uhlobo lwayo lwetyuwa ye-disodium lunyusa ukunyibilika kwayo kwizisombululo zamanzi, okwenza kube lula ngakumbi ukusetyenziswa kwilabhoratri.
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I-Ribonucleic acid evela kwi-Baker's Yeast CAS:63231-63-0
I-Ribonucleic acid (i-RNA) evela kwimvubelo kaBaker, ekwaziwa ngokuba yiSaccharomyces cerevisiae, ibhekisa kwiimolekyuli ze-RNA ezikhoyo kule fungus iqhelekileyo eneseli enye. Isebenza imisebenzi eyahlukeneyo ebalulekileyo kwiseli, kubandakanya ukwenziwa kweproteni, umsebenzi we-enzymatic, kunye nokulawulwa kwezakhi zofuzo. I-RNA evela kwimvubelo kaBaker inomdla koososayensi kunye nabaphandi abafunda ibhayoloji yeemolekyuli, izakhi zofuzo, kunye neenkqubo zeeseli. Isetyenziswa kuluhlu olubanzi lweemvavanyo kunye nezifundo ukuze kufunyanwe ulwazi malunga nokubonakaliswa kwezakhi zofuzo, ukucutshungulwa kwe-RNA, kunye neendlela zemolekyuli ezisisiseko semisebenzi yeeseli.
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I-6-Chloropurine CAS: 87-42-3 Ixabiso lomenzi
I-6-Chloropurine yikhemikhali eyinxalenye yosapho lwe-purine. Yinto evela kwi-purine, eyisiseko esibalulekileyo sokwakha i-DNA kunye ne-RNA. I-6-Chloropurine isetyenziswa kwi-organic synthesis kunye nophando lwe-pharmaceutical njengesandulela sokulungiselela i-purine derivatives ezahlukeneyo kunye nee-pharmaceutical compounds.
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Ityuwa ye-Adenosine 5′-monophosphate disodium CAS:4578-31-8
Ityuwa ye-disodium ye-Adenosine 5′-monophosphate, eyaziwa ngokuba yi-5′-AMP, yi-nucleotide equlathe i-adenine, i-ribose, kunye neqela le-phosphate. Isebenza njengomanduleli we-adenosine triphosphate (ATP), eyimolekyuli ebalulekileyo ebandakanyeka ekudlulisweni kwamandla eseli. Kuphando nakwizicelo ze-biochemical, i-5′-AMP isetyenziswa njengesiseko kwiimpendulo ze-enzyme, ngakumbi kwizifundo ze-metabolism ye-nucleotide, iindlela zokubonisa, kunye nenxalenye kwiimvavanyo ezahlukeneyo. Uhlobo lwayo lwetyuwa ye-disodium luphucula ukunyibilika kwayo kunye nokuzinza kwayo, okwenza ifaneleke ukusetyenziswa kovavanyo.
