I-IBMX, i-3-isobutyl-1-methylxanthine CAS:28822-58-4

I-3-isobutyl-1-methylxanthine, ekwaziwa ngokuba yi-IBMX, yi-methylxanthine derivative esetyenziswa kakhulu kuphando lwesayensi njengesithinteli esingangqalanga se-cyclic nucleotide phosphodiesterases. Iyaziwa ngokunyusa amanqanaba angaphakathi kweseli e-cyclic AMP (cAMP) kunye ne-cyclic GMP (cGMP) ngokuthintela ukuqhekeka kwazo, nto leyo enokuthi iguqule iindlela ezahlukeneyo zokubonisana kweeseli.

Ukongeza kwizicelo zayo zophando, i-IBMX isetyenzisiwe kwezinye iindawo zonyango ngenxa yemiphumo yayo ye-bronchodilator kunye ne-vasodilator. Nangona kunjalo, ukusetyenziswa kwayo kumayeza abantu kulinganiselwe.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

Isixhobo soPhando: I-IBMX isetyenziswa kakhulu kuphando lwesayensi ukunyusa amanqanaba e-cAMP kunye ne-cGMP ngaphakathi kweseli, isebenza njengesixhobo esibalulekileyo sokufunda iindlela zokubonisana zeseli, ukudluliselwa kwesignali, kunye nokuguqulwa kwe-pharmacological ye-cyclic nucleotides.

Izifundo zeKhemikhali: I-IBMX isetyenziswa kwizifundo zekhemikali ukuphanda imiphumo yamanqanaba aphezulu e-cAMP kunye ne-cGMP kumsebenzi weseli kunye neempendulo zomzimba.

Ukwahluka kwe-Adipocyte: I-IBMX yaziwa ngokuphucula ukwahluka kwe-preadipocytes zibe yi-adipocytes evuthiweyo, kwaye isetyenziswa rhoqo kunye nezinye iikhompawundi ukukhuthaza i-adipogenesis kwiimvavanyo zenkcubeko yeseli.

Iziphumo zeVasodilator kunye neBronchodilator: I-IBMX ibonakalisiwe ukuba ibonisa iziphumo zevasodilator kunye neBronchodilator, kwaye ifundwe malunga nokusetyenziswa okunokwenzeka konyango kwiimeko ezifana ne-asthma kunye noxinzelelo lwegazi lwemiphunga.

Ukuguqulwa komsebenzi we-Neuronal: I-IBMX iphandwe ngendima yayo ekulawuleni umsebenzi we-neuronal, ukudluliselwa kwe-synaptic, kunye nokwakheka kwe-plasticity kwinkqubo ye-nervous ephakathi.

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C10H14N4O2
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	28822-58-4
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.