I-Fmoc-Gln-OH CAS:118609-68-0

I-Fmoc-Gln-OH isebenza njengesixhobo esiguquguqukayo kwi-peptide synthesis, ngakumbi ekwenzeni iipeptides ezine-glutamine ngokuchanekileyo. Iqela elikhuselayo le-Fmoc likhusela iqela le-amino, liqinisekisa iimpendulo ezikhethiweyo ngexesha lokudibanisa i-peptide. Abaphandi basebenzisa kakhulu i-Fmoc-Gln-OH ekwenzeni iipeptides kwizicelo ezahlukeneyo, kubandakanya uphuhliso lwezonyango ezisekelwe kwi-peptide, izinto eziphilayo, kunye neepeptides ezineemotifs ezithile zesakhiwo. Ukuhambelana kwayo neendlela eziqhelekileyo zokwenziwa kwe-peptide, kuzo zombini izicwangciso zesigaba esiqinileyo kunye nesigaba sesisombululo, kuphucula ukuguquguquka kwayo kwimisebenzi eyahlukeneyo yophando. Ukususwa okulawulwayo kwamaqela akhuselayo kuvumela ukufakwa kwe-glutamine kwizicwangciso ze-peptide, kwandisa ububanzi beepeptides ezinokwenziwa. Ngaphezu koko, i-Fmoc-Gln-OH ifumana uncedo kwizifundo ezinxulumene nobunjineli beproteni, ii-peptide mimetics, kunye noyilo lwee-peptides ezisebenzayo. Ukusetyenziswa kwayo kwesicwangciso kwenza ukuba i-glutamine reactivity isebenze ngokuchanekileyo, inika abaphandi isixhobo esibalulekileyo sokuyila iipeptides ngohlengahlengiso olulungiselelweyo. Ngamafutshane, i-Fmoc-Gln-OH imele njengesixhobo esisisiseko nesingenamsebenzi kwi-peptide chemistry, inika amandla abaphandi ukuba baphonononge kwaye batshintshe i-glutamine reactivity kwiindidi ezahlukeneyo zezicelo zesayensi, ngakumbi begxile kwiipeptides eziqulethe le amino acid ibalulekileyo.