I-Fmoc -Glu(OBut)-OSu CAS:101214-22-6

I-Fmoc-Glu(OBut)-OSu ifumana uncedo olukhulu ekuhlanganiseni i-peptide, ngakumbi kwi-bioconjugation kunye nezicelo zokuthintela i-peptide. Uhlobo lwayo olusebenzayo njenge-N-hydroxysuccinimide ester luvumela iimpendulo zokudibanisa ezikhethiweyo kunye nama-amine aphambili akhoyo kwi-peptides, iiproteni, okanye iindawo eziphezulu. Abaphandi basebenzisa i-Fmoc-Glu(OBut)-OSu ukudibanisa ii-peptides kwiimolekyuli zokuthwala, iindawo eziphezulu, okanye ezinye ii-peptides, okwenza kube lula ukuphuhliswa kwezonyango ezisekelwe kwi-peptide, ukuxilongwa, kunye nezinto eziphilayo. Ngaphezu koko, i-Fmoc-Glu(OBut)-OSu isebenza njengesixhobo esibalulekileyo kuphando lwebhayoloji yamakhemikhali kunye ne-proteomics, okuvumela ukuguqulwa kweproteni okanye ii-peptides kwindawo ethile kwizifundo ezisebenzayo okanye ukucocwa kwe-affinity. Ukuhambelana kwayo neekhemikhali ezahlukeneyo zokudibanisa kunye neemeko zokuphendula ezithambileyo kuphucula ukuguquguquka kwayo kwizicelo ezahlukeneyo zophando. Ngaphezu koko, i-Fmoc-Glu(OBut)-OSu idlala indima ebalulekileyo ekuhlanganiseni ii-peptide mimetics, ii-peptide dendrimers, kunye nezinye izakhiwo ezintsonkothileyo ezisekelwe kwi-peptide. Ukulawulwa kwayo kunye nokuzinza kwayo kwenza ukuba ibe lukhetho olukhethwayo kwiimpendulo zokudibanisa iipeptide ezikhethayo, okuvumela abaphandi ukuba bayile ngokuchanekileyo izakhiwo zepeptide ezinemisebenzi eyenzelwe bona. Ngamafutshane, i-Fmoc-Glu(OBut)-OSu imi njengesixhobo esiguquguqukayo nesibalulekileyo kwikhemistri yepeptide, inika abaphandi amandla okwenza iimpendulo zokudibanisa iipeptide ezikhethiweyo kunye nokwandisa ububanzi bezicelo kuphando olusekelwe kwi-peptide, i-biotechnology, kunye nophuhliso lwamayeza.