I-GSSG CAS:27025-41-8 Ixabiso lomenzi

I-GSSG, eyaziwa ngokuba yi-oxidized glutathione, luhlobo lwe-disulfide lwe-antioxidant glutathione (GSH). Ngelixa i-GSH iluhlobo olunciphileyo nolusebenzayo, i-GSSG iluhlobo lwe-oxidized nelungasebenziyo. I-GSSG yenziwa xa i-GSH inikela ngee-electron zayo ukuze inciphise ii-free radicals okanye ezinye iintlobo ezisabelayo. Olu tshintsho lunceda ekukhuseleni umzimba kumonakalo we-oxidative. I-GSSG inokuguqulwa ibuyele kwi-GSH ngenkqubo yokuphinda isetyenziswe equka i-enzyme glutathione reductase. Ukubeka esweni umlinganiselo we-GSH kwi-GSSG emzimbeni kuluncedo ekuvavanyeni imeko ye-antioxidant kunye nempilo iyonke.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Biomarker yoxinzelelo lwe-oxidative: Ukubeka esweni umlinganiselo we-GSSG/GSH kunokusebenza njenge-biomarker yokuvavanya amanqanaba oxinzelelo lwe-oxidative emzimbeni. Amanqanaba aphezulu e-GSSG anxulunyaniswa nezifo ezahlukeneyo, kubandakanya izifo zentliziyo, iingxaki ze-neurodegenerative, kunye nomhlaza.

Uphando lwezeMithi: Ukufunda isiphumo se-GSSG kunye nempembelelo yaso kwimisebenzi yeseli kunokunceda ekuphuhlisweni kokungenelela kwezeMithi ukuze kulungiswe uxinzelelo lwe-oxidative. Ukujolisa ekusetyenzisweni kwakhona kwe-GSSG kunye nokulawula umlinganiselo we-GSH/GSSG kunokubonelela ngeengenelo zonyango kwiimeko ezahlukeneyo ze-pathological.

Unyango lwe-Antioxidant: Ukuqonda isiphumo se-GSSG kunokunceda ekuphuhlisweni konyango lwe-antioxidant. Ngokukhuthaza ukuphinda kusetyenziswe i-GSSG kwi-GSH okanye ukongeza izinto ezisandula ukwenziwa ze-GSH, ezifana ne-N-acetyl cysteine (NAC), kunokwenzeka ukubuyisela ibhalansi ye-redox, ukunciphisa uxinzelelo lwe-oxidative, kunye nokunciphisa izifo ezinxulumene noko.

Amaqhinga okulwa nokwaluphala: Uxinzelelo oluphezulu lwe-oxidative kunye nomlinganiselo we-GSH/GSSG ophazamisekileyo zinxulunyaniswa nenkqubo yokwaluphala. Ngokuqonda isiphumo se-GSSG, abaphandi banokuphonononga amaqhinga okugcina ibhalansi ye-redox yeselula kunye nokucothisa inkqubo yokwaluphala.

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C20H32N6O12S2
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	27025-41-8
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.