I-H-Asp(OBzl)-NH2·HCL CAS:199118-68-8

I-H-Asp(OBzl)-NH2·HCl idlala indima ebalulekileyo ekwenziweni kwe-peptide, apho iqela elikhusela i-benzyl ester linceda ukuthintela iimpendulo ezingafunekiyo ngexesha lokuhlanganiswa kwee-peptides eziqulethe ii-aspartic acid residues, ngelixa iqela le-amino lizisa ukuguquguquka ekuguquleni iipropati ze-peptide. Isetyenziswa kakhulu ekulungiseleleni ii-peptides eziguquliweyo zokufunda ukusebenzisana kweproteni-protein, ubudlelwane be-enzyme-substrate, kunye nokuhambelana kwesakhiwo-umsebenzi. Abaphandi bakwasebenzisa i-H-Asp(OBzl)-NH2·HCl ekuphuhlisweni kwamayeza asekelwe kwi-peptide kwaye njengebhloko ebalulekileyo yokwakha ii-peptides ezintsha kunye ne-peptidomimetics ezinezicelo zonyango ezinokubakho. Ngaphezu koko, le reagent ifumana ukusetyenziswa ekwenziweni kwe-peptide yesigaba esiqinileyo, indlela esisiseko kwi-peptide chemistry kunye nemizamo yokufumanisa iziyobisi. Uncedo lwayo lufikelela kuphando kwi-bioconjugation kunye ne-chemical biology, okwenza kube lula ukuhlanganiswa kwee-peptides kwezinye iimolekyuli ukuze kunikezelwe okanye kuhlolwe. Ngaphezu koko, i-H-Asp(OBzl)-NH2·HCl inegalelo ekuphuculeni ukuqonda kwethu ubudlelwane bolwakhiwo lwe-peptide nomsebenzi kwaye isebenza njengecandelo elibalulekileyo ekuphononongeni iinkalo ezahlukeneyo zesayensi ye-peptide. Ngokubanzi, isebenza njengesixhobo esibalulekileyo, esivumela abaphandi ukuba bahlolisise ubunzima be-peptide chemistry kunye nemiphumo yayo kuphando lwe-biomedical, uphuhliso lwamayeza, kunye nokungenelela okunokwenzeka konyango.