H-Gly-OBzl·Tos CAS:1738-76-7

I-H-Gly-OBzl·Tos idlala indima ebalulekileyo ekwakhiweni kwe-peptide, isebenza njengebhloko ebalulekileyo yokwakha ii-peptides ezineempawu ezithile zesakhiwo kunye nokusebenza. Iqela le-benzyl ester kunye neqela elikhusela i-tosyl liqinisekisa ukuba intsalela ye-glycine ihlala ingatshintshi ngexesha leenkqubo zokwenziwa kwe-peptide, okuvumela ukuhlanganiswa kwe-peptide ngokuchanekileyo nangokulawulwayo. Le khompawundi ibalulekile ekuyileni ii-peptides ezineempawu ezilungiselelweyo ezifana nokuzinza okuphuculweyo, ukufumaneka kwezinto eziphilayo, okanye ukumelana nokuwohloka kwe-enzyme, okwenza ukuba ibe sisixhobo esibalulekileyo kuphuhliso lwamayeza, ngakumbi ekudaleni amayeza asekelwe kwi-peptide. Ukongeza kwindima yayo ekwakhiweni kwe-peptide, i-H-Gly-OBzl·Tos ifumana isicelo kuphando lwe-proteomics kunye ne-biochemical, apho inokusetyenziswa khona ukufunda ukusebenzisana kweproteni-protein, ukuphanda umsebenzi we-enzyme, kunye nokuphonononga amandla okugoba kweproteni. Ulwakhiwo lwayo olulungiselelweyo luvumela abaphandi ukuba baphonononge ubunzima beenkqubo zeseli kunye neendlela zesifo, okufaka isandla ekuphuculeni ukuqonda impilo kunye ne-pathology. Ukuguquguquka kunye nokuhambelana kwekhompawundi neemeko ezahlukeneyo zovavanyo kwenza ukuba ibe yinxalenye ebalulekileyo yokutyhila ubunzima beenkqubo zebhayoloji kunye nokuphuhlisa iindlela zokungenelela ezijolise kwiimeko ezahlukeneyo zonyango. Ngamafutshane, i-H-Gly-OBzl·Tos imele isixhobo esibalulekileyo kubaphandi kwi-peptide synthesis, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, enika amandla okulungelelanisa iipeptides ezineempawu ezithile kunye nokusombulula iindlela ezisisiseko zeenkqubo zebhayoloji, ngaloo ndlela inegalelo ekuphuculeni amayeza kunye ne-biotechnology.