H-Ile-OBut·HCl CAS:69320-89-4

I-H-Ile-OBut·HCl idlala indima ebalulekileyo ekuqulunqweni kwe-peptide njengesiseko esibalulekileyo sokwakha ii-peptides ezineempawu ezithile zesakhiwo kunye nokusebenza. Ubukho beqela le-tert-butyl ester buvumela ukunxibelelana okuphuculweyo kwe-hydrophobic kwaye buchaphazela ukusebenza kwe-chemical kwe-peptide, okwenza ibe luncedo ekuyileni ii-peptides ezinokuphucula ukuvuleka kwe-membrane okanye iipropati zokuhambisa ezijolise kuzo. Ekuphuhlisweni kwamayeza, le khompawundi ingasetyenziselwa ukwenza amayeza asekelwe kwi-peptide anozinzo oluphuculweyo kunye nokufumaneka kwezinto eziphilayo, okunokukhokelela ekusebenzeni ngcono konyango, ngakumbi ngenxa yesimo sayo se-HCl. Ngaphezu koko, kuphando lwe-proteomics kunye ne-biochemical, i-H-Ile-OBut·HCl ifumana isicelo ekufundeni ukusebenzisana kweproteni-protein, ukuphanda imisebenzi ye-enzyme, kunye nokuphonononga iindlela zokubonisa iiseli. Ulwakhiwo lwayo olulungiselelweyo luvumela abaphandi ukuba baphonononge ubunzima beenkqubo zeseli kunye neendlela zesifo, okufaka isandla ekuphuculeni ukuqonda impilo kunye ne-pathology. Ukuguquguquka kunye nokuhambelana kwekhompawundi neemeko ezahlukeneyo zovavanyo kwenza ukuba ibe yinxalenye ebalulekileyo yokutyhila ubunzima beenkqubo zebhayoloji kunye nokuphuhlisa iindlela zokungenelela ezijolise kwiimeko ezahlukeneyo zonyango. Ngamafutshane, i-H-Ile-OBut·HCl imele isixhobo esibalulekileyo kubaphandi kwi-peptide synthesis, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, enika amandla okulungisa iipeptides ezineempawu ezithile kunye nokuvula iindlela ezisisiseko zeenkqubo zebhayoloji, ngaloo ndlela inegalelo ekuqhubekeni phambili kwezonyango kunye ne-biotechnology.