I-H-Ile-OMe·HCl CAS:18598-74-8

I-H-Ile-OMe·HCl isebenza njengebhloko ebalulekileyo ekwakheni iipeptide, idlala indima ebalulekileyo ekwakheni iipeptide ezineempawu ezithile zesakhiwo kunye nokusebenza. Ubukho beqela le-methyl ester buchaphazela ukusebenza kweekhemikhali kunye nokusebenzisana kwe-hydrophobic kwepeptide, okwenza ibe luncedo ekuyileni iipeptides ezinokuphucula ukuvuleka kwe-membrane okanye izakhono ezithile zokujolisa. Le compound ibalulekile ekudaleni iipeptides ezineempawu ezilungiselelweyo ezifana nokuzinza okuphuculweyo, ukunyibilika, okanye ukufumaneka kwezinto eziphilayo, okwenza ibe sisixhobo esibalulekileyo kuphuhliso lwamayeza. Ukongeza kwindima yayo ekuhlanganisweni kweepeptide, i-H-Ile-OMe·HCl ifumana isicelo kwi-proteomics kunye nophando lwe-biochemical, apho inokusetyenziswa khona ukufunda ukusebenzisana kweeprotein-protein, ukuphanda imisebenzi ye-enzyme, kunye nokuphonononga iindlela zokubonisa iiseli. Iimpawu zayo ezikhethekileyo zivumela abaphandi ukuba baphonononge ubunzima beenkqubo zeseli kunye neendlela zesifo, zinegalelo ekuqhubekeni kokuqonda impilo kunye ne-pathology. Ukuguquguquka kunye nokuhambelana kwekhompawundi neemeko ezahlukeneyo zovavanyo kwenza ukuba ibe yinxalenye ebalulekileyo yokutyhila ubunzima beenkqubo zebhayoloji kunye nokuphuhlisa iindlela zokungenelela ezijolise kwiimeko ezahlukeneyo zonyango. Ngamafutshane, i-H-Ile-OMe·HCl imele isixhobo esibalulekileyo kubaphandi kwi-peptide synthesis, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, enika amandla okulungisa iipeptides ezineempawu ezithile kunye nokusombulula iindlela ezisisiseko zeenkqubo zebhayoloji, ngaloo ndlela inegalelo ekuqhubekeni phambili kwezonyango kunye ne-biotechnology.