I-N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umthengisi woMvelisi

N-I-Acetyl-D-Glucosamine yi-N-acetyl derivative ye-glucosamine. Ngokwekhemikhali yi-amide phakathi kwe-glucosamine kunye ne-acetic acid. Inxalenye enye ye-N-acetlyglucosamine edibene ne-serine okanye i-threonine residues kwiiproteni zenyukliya kunye ne-cytoplasmic -O-GlcNAc, lutshintsho lweproteni olufumaneka rhoqo emva kokuguqulwa. Iiproteni eziguqulweyo ze-O-GlcNAc zibandakanyeka ekuboneni imeko yesondlo sendawo ejikelezileyo yeseli kunye nokulungisa umsebenzi weeproteni zeseli ngokufanelekileyo. I-O-GlcNAc ilawula iimpendulo zeseli kwiihomoni ezifana ne-insulin, iqalisa impendulo yokukhusela kuxinzelelo, iguqula amandla eseli okukhula nokwahlukana, kwaye ilawula ukubhalwa kwezakhi zofuzo. Kubantu, ikhona eluswini, kwi-cartilage nakwimithambo yegazi njengenxalenye ye-hyaluronic acid, nakwizicubu zethambo, kwi-cornea nakwi-aorta njengenxalenye ye-keratan sulfate.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-N-Acetyl-D-glucosamine isetyenziswa ekuchongeni nasekuchazeni i-N-acetyl-beta-D-hexoaminidase. Ikwasetyenziswa kunyango lwe-osteoarthritis kunye nesifo samathumbu esivuthayo (IBD), kubandakanya i-ulcerative colitis kunye nesifo sikaCrohn. Ngaphezu koko, isetyenziswa njengesiseko kwimveliso ye-sialic acid, izinto zokuthambisa kunye nophando lophuhliso lwamayeza. I-N-acetyl-D-Glucosamine (GlcNAc) sisiphumo se-monosaccharide seglucose. Ikhutshwa yintshukumo ye-O-GlcNAcase, kwiinkqubo zezilwanyana ezincancisayo ezivela kwiiproteni eziguqulwe emva kokuguqulelwa nge-O-GlcNAc. Amanqanaba eeproteni ze-O-GlcNAcylation ezivela kwi-Alzheimer's disease brain extracts ayancipha xa kuthelekiswa nalawo akwii-controls, nto leyo ebonisa ukuba ukukhululwa kwe-GlcNAc kunokubangela i-pathogenesis.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C8H15NO6
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe ukuya komhlophe ongekho mhlophe
Inombolo ye-CAS	7512-17-6
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.