I-Teduglutide CAS:197922-42-2 Umthengisi woMvelisi

I-Teduglutide (ekwaziwa ngokuba yi-ALX-0600) yi-analogue ye-GLP-2 apho i-glycine ithathelwe indawo yi-alanine kwindawo yesi-2 ukusuka kwi-N-terminus, ngaloo ndlela inika ukumelana nokuwohloka yi-DPP-4. I-Teduglutide inobuhlobo obufanayo bokubopha, amandla e-agonist, kunye nokusebenza kakuhle kwe-agonist njenge-GLP-2 kwiimvavanyo kunye ne-receptor ye-GLP-2 yegundane. Ukunikezelwa kwe-teduglutide kwiimpuku kunike ukonyuka okukhulu kubunzima bamathumbu amancinci kunye nokunyuka kokuphakama kwe-intestinal villi. I-Teduglutide yalungiswa ngokwenziwa kwe-peptide yesigaba esiqinileyo.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Teduglutide yi-peptide hormone esetyenziselwa ukunyanga izigulana zabantwana ngendlela esebenzayo ixesha elide. Ibonakalisiwe ukuba iyasebenza kunyango lwezifo zokuzikhusela komzimba kunye nesifo samathumbu. Yi-analogue esebenza ixesha elide ye-glucagon-like peptide 1 (GLP-1). Eli yeza libonakalisiwe linozinzo oluphezulu lweekhemikhali, oko kuthetha ukuba aliqhekeki lula. I-Teduglutide ifakwa emzimbeni kwaye ithathwe ziiseli, apho isebenza khona ii-receptors kumphezulu weeseli. Oku kusebenza kukhokelela ekuvelisweni kweglucose yisibindi kunye nokuphucula uvakalelo lwe-insulin kwizicubu ezingaphandle ezifana nezihlunu, amafutha, nesibindi. Ikwanyusa izinga lentliziyo kunye noxinzelelo lwegazi.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C164H252N44O55S
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe ukuya kongamhlophe
Inombolo ye-CAS	197922-42-2
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.