I-Trt-Cys(Trt)-OH · I-DEA CAS:27486-88-0

I-Trt-Cys(Trt)-OH·DEA idlala indima ebalulekileyo ekuqulunqweni kwe-peptide, ngakumbi ekulungiseleleni ii-peptides eziqulathe i-cysteine ​​ezibaluleke kakhulu kuphononongo lokusebenzisana kweproteni neproteni, ubudlelwane be-enzyme-substrate, kunye nokuhambelana kwesakhiwo nomsebenzi. Iqela le-trityl lisebenza njengeqela elikhuselayo lokusebenza kwe-thiol ye-cysteine, okuvumela ukunqunyulwa kokukhusela okukhethiweyo ngexesha lokuhlanganiswa kwe-peptide. Ngaphezu koko, le compound ifumana ukusetyenziswa ekuqulunqweni kwe-peptide yesigaba esiqinileyo, indlela esisiseko kwi-peptide chemistry kunye nemizamo yokufumanisa iziyobisi, evumela uphuhliso lwee-peptides ezintsha kunye ne-peptidomimetics kunye nezicelo zonyango ezinokubakho. Ngaphezu koko, i-Trt-Cys(Trt)-OH·DEA inegalelo ekuphuculeni ukuqonda kwethu ubudlelwane besakhiwo nomsebenzi we-peptide kwaye isebenza njengecandelo elibalulekileyo ekuphononongweni kweempawu ezahlukeneyo zesayensi ye-peptide. Uncedo lwayo lufikelela kuphando kwi-bioconjugation kunye ne-chemistry biology, oluququzelela ukuhlanganiswa kwee-peptides kwezinye iimolekyuli ukuze kunikezelwe okanye kuchongwe iinjongo. Lilonke, isebenza njengesixhobo esibalulekileyo, esenza abaphandi bakwazi ukuphonononga ubunzima be-peptide chemistry kunye neziphumo zayo kuphando lwezonyango, uphuhliso lwamayeza, kunye nokungenelela okunokwenzeka konyango. Ngezicelo zayo ezibanzi kuphando lwe-peptide, le reagent ixabisa kakhulu ekuphuculeni ulwazi lwesayensi kunye negalelo kuphuhliso lwezonyango ezisekelwe kwi-peptide.