I-Venlafaxine CAS:93413-69-5

IVenlafaxine sisithomalalisi sokudakumba seklasi ye-serotonin kunye ne-norepinephrine reuptake inhibitor (SNRI). Eli yeza laqalwa ukuphuhliswa nguWyeth kwi-19Chemicalbook93 kwaye ngoku lithengiswa yiPfizer. Eli yeza livunyiwe ukunyanga isifo sokudakumba esikhulu (MDD), isifo sokudakumba esiqhelekileyo (GAD), kunye nokudakumba okunxulunyaniswa nexhala.

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Ukusetyenziswa kunye nesiphumo

I-Venlafaxine inokuthintela ukuphinda kuthathwe kwe-NA kunye ne-5-HT, kwaye ithintele kancinci ukuphinda kuthathwe kwe-dopamine. Ukuthintela i-cholinergic receptors kwi-in vitro, ii-histamine receptors α Zombini ii-receptors azinawo amandla. Ukufunxwa kwesisu kulungile, kwaye iChemicalbook inyibilikiswa yi-cytochrome P45011D6 esibindini kwaye ikhutshwa ngumchamo. I-t1/2 yee-metabolites eziphambili ezisebenzayo isusela kwiiyure ezi-5 ukuya kwezili-11. Emva kweeveki ezi-3, uxinaniso oluzinzileyo lufikelelwe. Isetyenziselwa unyango lokudakumba.

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Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C17H27NO2
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe wekristale
Inombolo ye-CAS	93413-69-5
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.