I-Wortmannin CAS:19545-26-7 Ixabiso lomenzi

I-Wortmannin yikhemikhali yendalo esetyenziswa rhoqo kuphando lwelabhoratri ukufunda iinkqubo ezahlukeneyo zeseli. Sisithinteli esinamandla se-phosphoinositide 3-kinase (PI3K), i-enzyme ebandakanyeka kwiindlela ezahlukeneyo zokuhambisa imiyalezo ngaphakathi kweeseli.

Ngokuthintela i-PI3K, i-wortmannin inokuthintela ngempumelelo umsebenzi weemolekyuli zokubonisa ezisezantsi kunye neendlela ezixhomekeke kwi-PI3K. Oku kuvumela abaphandi ukuba baphande indima edlalwa yi-PI3K kunye neendlela ezinxulumene nayo kwiinkqubo ezinje ngokukhula kweeseli, ukwanda, i-apoptosis, ukurhweba ngaphakathi kweeseli, kunye ne-membrane dynamics.

I-Wortmannin isetyenzisiwe kakhulu kwizifundo ukuqonda iindlela ze-molecular zezifo ezahlukeneyo, kubandakanya umhlaza, ukudumba, iingxaki zokuzikhusela komzimba, kunye nezifo eziwohlokayo kwimithambo-luvo. Inokunceda abaphandi ukuba bachonge iinjongo zonyango ezinokubakho kwaye baphuhlise amaqhinga amatsha okunyanga ezi meko.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

Ukuqonda umhlaza: Umqondiso we-PI3K uhlala ungalawuleki kwiiseli zomhlaza, nto leyo ekhokelela ekukhuleni nasekuphileni kweeseli okungalawulekiyo. I-Wortmannin isetyenziselwe ukufunda indima ye-PI3K ekuphuhlisweni komhlaza, ukuqhubela phambili, kunye nokunganyamezelani nonyango.

Ukuphanda ukudumba: I-PI3K signaling ikwabandakanyeka ekulawuleni iimpendulo zomzimba kunye nokudumba. I-Wortmannin isetyenzisiwe ukuphonononga iindlela ezichanekileyo i-PI3K enegalelo ngazo ekudumbeni kunye nokuchonga iinjongo ezinokubakho zokungenelela kokudumba.

Ukufunda nge-autophagy: I-Autophagy yinkqubo yeselula equka ukonakala kunye nokurisayikilisha izinto zeseli. Iindlela ze-PI3K zokubonisa zidlala indima ebalulekileyo ekulawuleni i-autophagy. I-Wortmannin isetyenziselwe ukuphanda igalelo elithile le-PI3K kwi-autophagy kunye nokuchonga iindlela zayo ze-molecular.

Ukuhlola izifo ezibangela ukonakala kwemithambo-luvo: I-PI3K signaling ibandakanyeka kwizifo ezininzi ezibangela ukonakala kwemithambo-luvo, ezifana nesifo sika-Alzheimer kunye nesifo sikaParkinson. I-Wortmannin isetyenziselwe ukufunda ukubandakanyeka kwe-PI3K kwi-pathogenesis yezi zifo kunye nokuchonga iinjongo zonyango ezinokubakho.

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C23H24O8
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	19545-26-7
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.