I-Z-MeVal-OH CAS:42417-65-2

Le mveliso isetyenziswa kakhulu ngabaphandi kunye neenkampani zamayeza ekwenziweni kweepeptides eziqulethe iintsalela ze-N-methylvaline. I-N-methylvaline yaziwa ngokukwazi kwayo ukuphucula uzinzo lokwakheka kunye nokuvuleka kwe-membrane yeepeptides, okwenza ukuba ibe sisakhiwo esibalulekileyo ekuphuhlisweni kwamayeza kunye nezonyango ezisekelwe kwi-peptide. I-Z-MeVal-OH icocekile kakhulu kwaye iyahambelana nezinye ii-reagents, nto leyo eyenza ukuba ibe lukhetho oluthembekileyo kwiiprojekthi zokwenziwa kweepeptide. I-Z-MeVal-OH sisixhobo esiguquguqukayo kubaphandi kwicandelo le-biochemistry, i-pharmacology, kunye nokufunyanwa kwamayeza. Uzinzo lwayo, ubunyulu, kunye nokuhambelana kwayo kwenza ukuba ibe yinxalenye ebalulekileyo ekwenziweni kweepeptides eziqulethe i-N-methylvaline, ezinezicelo ezinokubakho kuphuhliso lwamayeza, uphando lwebhayoloji, kunye nokungenelela konyango. Ngokufaka i-Z-MeVal-OH kulandelelwano lweepeptide, abaphandi banokwenza iikhompawundi ezintsha ezineempawu ze-bioactivity eziphuculweyo kunye ne-pharmacokinetic, ziqhubele phambili icandelo lokufunyanwa kwamayeza asekelwe kwi-peptide.