I-1,4-Dithioerythritol (DTE) CAS:6892-68-8

I-Agent yokunciphisa: I-DTE isetyenziswa kakhulu ukuqhekeza iibhondi ze-disulfide kwiimolekyuli. Inganciphisa iikhompawundi ezine-disulfide kwimo yazo ye-thiol, ivumela abaphandi ukuba bafunde imeko ephantsi yeeproteni, iipeptides, kunye nezinye ii-biomolecules. Oku kuluncedo ngakumbi ekucoceni iiproteni kunye nokulungiselela isampuli, njengoko kunceda ukuthintela ukuhlanganiswa kweeproteni kunye nokugcina uzinzo lweeproteni.

Ukuguquka kweProtein: I-DTE ingasetyenziselwa ukuphazamisa ukwakheka kweprotein ngokuphazamisa isakhiwo sayo sesithathu. Oku kuluncedo kwizifundo zeprotein apho kufuneka ukuvuleka nokugoba kwakhona, njengokufumanisa i-kinetics yokugoba kweprotein okanye ukuphanda ukusebenzisana kweprotein neprotein.

I-Antioxidant: I-DTE ineempawu ze-antioxidant kwaye inokususa ii-free radicals kunye ne-reactive oxygen species (ROS). Inceda ekukhuseleni iiseli kunye nee-biomolecules kumonakalo we-oxidative obangelwa yi-ROS. I-DTE ingasetyenziswa kwiimvavanyo zenkcubeko yeseli ukufunda imiphumo yoxinzelelo lwe-oxidative kwiiseli kunye nokuvavanya umsebenzi we-antioxidant.

Izifundo zokuThintela ii-Enzyme: I-DTE idla ngokusetyenziswa njengolawulo olungalunganga okanye umthinteli kwizifundo zokuThintela ii-enzyme. Ngokuthintela ngokungenakuguquguquka indawo esebenzayo ye-enzyme, inceda abaphandi ukuba bamisele ubunyani kunye nendlela yokuthintela ii-enzyme ngamanye amakhompawundi.

Ukwenziwa kweekhemikhali: I-DTE ingasetyenziswa kwi-chemical synthesis njenge-reducing agent yokuguqula ii-carbonyl compounds zibe zii-alcohols zazo ezifanelekileyo. Iluncedo ngakumbi kwi-asymmetric synthesis, apho kufuneka i-stereoselectivity.