I-Candesartana Cilexetila CAS:145040-37-5

ICendesartan Celexetil yi-ester analog ye-angiotensin II antagonist ICendesartan (sc-217825). Ukuchasana kwale receptor kuthintela ukubopha kwe-angiotensin II, i-vasoconstrictor enamandla. Oku kunefuthe elipheleleyo lokusasazeka kwemithambo yegazi kunye nomthamo wegazi onyukayo. ICendesartan Celexetil Ester sisithinteli se-AT1.

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Ukusetyenziswa kunye nesiphumo

I-Candesartan cilexetil sisithako se-angiotensin II type 1 receptor antagonist enamandla, esebenza ixesha elide, kwaye ekhethayo, i-candesartan. Ifakwa ngokukhawuleza kwi-candesartan ngexesha lokufunxwa kwesisu. Emva kokufunxwa kwe-candesartan cilexetil kwi-candesartan ngexesha lokufunxwa kwesisu, i-candesartan ikhuphisana ngokukhethekileyo ne-angiotensin II ekubopheni i-angiotensin II receptor subtype 1 AT1 kwimisipha egudileyo yemithambo yegazi, ithintela ukuxinana kwemithambo yegazi okubangelwa yi-angiotensin II kunye nokukhuthaza ukunwebeka kwemithambo yegazi. Ukongeza, ukuchasana kwe-AT1 kwi-adrenal gland kuthintela ukwenziwa kwe-aldosterone ekhuthazwa yi-angiotensin II kunye nokukhutshwa yi-adrenal cortex; ukukhutshwa kwe-sodium namanzi kuyanda, kulandelwa kukwehla komthamo weplasma kunye noxinzelelo lwegazi.

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Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C33H34N6O6
Uvavanyo	99%
Inkangeleko	Umgubo oMhlophe
Inombolo ye-CAS	145040-37-5
Ukupakisha	1KG 25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.