Abavelisi beekhemikhali ezilungileyo kunye nababoneleli - I-China Fine Chemical Factory

I-Fludarabine Phosphate CAS: 75607-67-9

I-Fludarabine phosphate yi-adenosine eyenziweyo, esetyenziswa kakhulu kunyango lwe-hematological malignancies efana ne-chronic lymphocytic leukemia (CLL) kunye ne-non-Hodgkin lymphoma. Isebenza ngokuphazamisa ukwenziwa kunye nokulungiswa kwe-DNA, ekugqibeleni ikhokelela kwi-apoptosis ekwahluleni iiseli zomhlaza ngokukhawuleza. Inikwa ngemithambo okanye ngomlomo, i-fludarabine phosphate ibonisa iipropati zokuthintela amasosha omzimba, nto leyo eyenza ukuba isebenze kwiimeko ezithile kodwa ikwafuna nokubekwa esweni ngononophelo kweziphumo ezimbi. Ukungeniswa kwayo kubonisa inkqubela phambili ebalulekileyo kwi-chemotherapy, ibonelela ngendlela ejolise kuyo eye yaphucula iziphumo kwizigulane ezininzi ezineemhlaza ezithile zegazi.

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i-o-Toluic acid CAS:118-90-1

I-o-Toluic acid, ekwaziwa ngokuba yi-ortho-toluic acid, yi-aromatic carboxylic acid ene-molecular formula C₈H₈O₂. Iquka iqela le-methyl kunye neqela le-carboxylic acid eliqhotyoshelwe kwiiathom zekhabhoni ezikufutshane kwindandatho ye-benzene, enika iipropati ezahlukeneyo zeekhemikhali kunye nokusebenza kwayo. Le khompawundi ikhona njenge-solid engenambala kwaye iyanyibilika kwi-organic solvents. I-o-Toluic acid isebenza njenge-intermediate ebalulekileyo ekuhlanganisweni kweekhemikhali ezahlukeneyo, kubandakanya iidayi, amayeza, kunye neekhemikhali zezolimo. Ulwakhiwo lwayo olwahlukileyo kunye namaqela asebenzayo aququzelela iimpendulo ezininzi, okwenza ukuba ibe luncedo kwiindawo zoshishino nakwilebhu.

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I-Glycinonitrile hydrochloride CAS: 6011-14-9

I-Glycinonitrile hydrochloride yikhemikhali enefomula yemolekyuli i-C₂H₄ClN₃, equlathe i-glycine derivative equka iqela elisebenzayo le-nitrile. Le kristale solid emhlophe yaziwa ngokusetyenziswa kwayo okunokwenzeka kwi-organic synthesis kunye ne-medicine chemistry. I-Glycinonitrile ingasebenza njengebhloko yokwakha eguquguqukayo ekuhlanganiseni iimolekyuli ezahlukeneyo ezisebenzayo kwibhayoloji, kubandakanya amayeza kunye neekhemikhali zezolimo. Iimpawu zayo ezikhethekileyo ziyenza ibe ngumviwa onomtsalane wophando olongezelelweyo kunye nophuhliso, ngakumbi kuyilo lweekhompawundi ezinemisebenzi ethile ye-pharmacological.

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I-Vinylene carbonate CAS:872-36-6

I-Vinylene carbonate (VC) yi-cyclic carbonate compound ene-molecular formula C₃H₄O₃. Ibonakaliswa liqela layo le-vinyl kunye neqela elisebenzayo le-carbonyl, okwenza ukuba ibe yi-monomer esabela kakhulu kwi-organic chemistry. I-VC isetyenziswa kakhulu njenge-electrolyte additive kwiibhetri ze-lithium-ion, apho iphucula ukwakheka kwe-stable solid electrolyte interphase (SEI), iphucula ukusebenza kwebhetri kunye nobomi bayo. Ukongeza, i-vinylene carbonate isebenza njengebhloko yokwakha iipolymerizations ezahlukeneyo kunye nokuhlanganiswa kweekhemikhali, igxininisa ngakumbi ukubaluleka kwayo kwisayensi yezinto kunye nokuhlanganiswa kwezinto eziphilayo.

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I-Disodium 5′-Guanylate CAS: 5550-12-9

I-Disodium 5′-guanylate, eyaziwa ngokuba yi-GMP, sisiphumo se-nucleotide esidlala indima ebalulekileyo kwiinkqubo ezahlukeneyo ze-biochemical ngaphakathi kwezinto eziphilayo. Njengesongezelelo sokutya kunye nesiphuculi sencasa, idla ngokusetyenziswa kunye ne-monosodium glutamate (MSG) ukuphucula incasa ye-umami kwizicelo zokupheka. I-GMP isebenza njengemolekyuli yokubonisa ebandakanyeka kunxibelelwano lweseli kunye nolawulo lwe-metabolic, ichaphazela iinkqubo ezifana nokuhlanganiswa kweproteni kunye ne-metabolism yamandla. Ngaphezu koko, isetyenziswa kuphando lwebhayoloji ye-molecular njenge-substrate kunye ne-activator kwiimpendulo ezahlukeneyo ze-enzyme, igxininisa ukubaluleka kwayo ngaphaya kwendima yayo ekuphuculeni incasa.

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i-p-Toluic acid CAS:99-94-5

I-p-Toluic acid, ekwaziwa ngokuba yi-para-toluic acid, yi-aromatic carboxylic acid ene-molecular formula C₈H₈O₂. Iqulathe i-toluene derivative apho iqela le-carboxyl (-COOH) kunye neqela le-methyl (-CH₃) zibekwe kumacala ahlukeneyo endandatho ye-benzene. Olu lungiselelo lwesakhiwo lubonelela ngeempawu ezahlukeneyo zeekhemikhali kunye nokusebenza kwakhona. I-p-Toluic acid ibonakala njenge-white crystalline solid kwaye iyanyibilika kwi-organic solvents. Isebenza njenge-intermediate ebalulekileyo ekuhlanganisweni kweekhemikhali ezahlukeneyo, kubandakanya iidayi, amayeza, kunye neekhemikhali zezolimo, ibonisa ukuguquguquka kwayo kunye nokubaluleka kwayo kwizicelo zoshishino nezelebhu.

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I-N,N'-Diaminoguanidine monohydrochloride CAS:36062-19-8

I-N,N'-Diaminoguanidine monohydrochloride (DGH) yikhompawundi yendalo enefomyula i-C₂H₈ClN₄, equlathe i-guanidine derivative equka amaqela amabini e-amine. Le khemikhali eguquguqukayo isetyenziswa kakhulu kwizicelo zamayeza, ngakumbi njengesandulela ekuhlanganisweni kweemolekyuli ezahlukeneyo ezisebenzayo kunye namayeza. I-DGH ifumene ingqalelo kwiipropati zayo zonyango ezinokubakho, kubandakanya ukusetyenziswa kunyango lweemeko ezithile zonyango ezifana nesifo seswekile kunye nezifo zokuphefumla. Ulwakhiwo lwayo olwahlukileyo luyivumela ukuba ithathe inxaxheba kwiimpendulo ezibalulekileyo ze-biochemical, igxininisa ukubaluleka kwayo kwikhemistri yamayeza kunye nophuhliso lwamayeza.

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I-Capecitabine CAS:154361-50-9

I-Capecitabine liyeza le-chemotherapy elisetyenziswa ngomlomo elisetyenziselwa ukunyanga iintlobo ezahlukeneyo zomhlaza, kuquka umhlaza we-colorectal kunye nomhlaza webele. Liyeza eliguqulwa libe yi-5-fluorouracil (5-FU), emzimbeni, elisebenzisa imiphumo yalo yokulwa nomhlaza ngokuthintela ukwenziwa kwe-DNA kunye nokuphazamisa umsebenzi we-RNA kwiiseli ezahlulahlula ngokukhawuleza. I-Capecitabine idla ngokusetyenziswa kunye nezinye iiarhente ze-chemotherapeutic ukuphucula ukusebenza kakuhle. Ukufakwa kwayo ngomlomo kunika enye indlela elula yonyango lwe-intravenous, ukuphucula ukunamathela kwesigulane. Nangona ngokubanzi inyamezelwa kakuhle, i-capecitabine inokubangela iziphumo ebezingalindelekanga ezifana ne-hand-foot syndrome, isicaphucaphu, kunye ne-myelosuppression.

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4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone CAS:166524-64-7

I-4(1H)-Pyrimidinone, 5-fluoro-2-methoxy-, i-hydrazone yikhompawundi ekhethekileyo yendalo ebonakaliswa bubukho bendandatho ye-pyrimidinone kunye nokusebenza kwe-hydrazone. Ngefomula yemolekyuli i-C₉H₁₀FN₃O₂, le khompawundi ine-athomu ye-fluorine kunye neqela le-methoxy elinegalelo kwiipropati zayo zeekhemikhali ezikhethekileyo. Ii-Hydrazones zaziwa ngokusebenza kwazo kunye nokusebenza kwazo kwizicelo ezahlukeneyo zokwenziwa kwezinto eziphilayo. Ngenxa yesakhiwo sayo, le khompawundi inefuthe elinokubakho kwikhemistri yamayeza, ngakumbi njengesandulela okanye esiphakathi kuphuhliso lweemolekyuli ezisebenzayo eziphilayo ezinokubaluleka konyango.

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I-3-Methylsalicylic acid CAS: 83-40-9

I-3-Methylsalicylic acid, ekwaziwa ngokuba yi-3-(methyl)salicylic acid okanye i-3-methyl-2-hydroxybenzoic acid, yi-compound enuka kamnandi ene-molecular formula C₈H₈O₃. Iquka iqela le-hydroxyl (-OH) kunye neqela le-carboxylic acid (-COOH) encamathele kwindandatho ye-benzene, ecaleni kweqela le-methyl elibekwe kwi-meta kwiqela le-hydroxyl. Olu lungiselelo lwesakhiwo lunika iipropati ezikhethekileyo zeekhemikhali ezenza ukuba ibe luncedo kwizicelo ezahlukeneyo. I-3-Methylsalicylic acid isetyenziswa kwi-organic synthesis, kwi-pharmaceuticals, nakwi-building block yezinye ii-compounds. Imisebenzi yayo yebhayoloji igxininisa ukubaluleka kwayo kwi-medical chemistry kunye nophando.

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(+)-5-Iodo-2′-deoxyuridine CAS:54-42-2

(+)-5-Iodo-2′-deoxyuridine (IUdR) yi-deoxyuridine analog ye-deoxyuridine eyenziweyo, equka i-athomu ye-iodine kwindawo yesi-5 yeringi ye-uracil. Njenge-arhente yokulwa neentsholongwane kunye nomhlaza, i-IUdR ifundwe ngenxa yokukwazi kwayo ukuthintela ukwenziwa kwe-DNA kwiiseli ezahlulahlula ngokukhawuleza, nto leyo eyenza ukuba ibe luncedo ngakumbi kuphando lomhlaza kunye namaqhinga okunyanga. Isebenza ngokuphazamisa inkqubo eqhelekileyo yokuphindaphinda kwe-DNA, nto leyo ekhokelela ekufeni kweeseli kwizicubu ezine-neoplastic. Ukongeza, i-IUdR isetyenziswa kunyango olwahlukeneyo lovavanyo, kubandakanya i-brachytherapy yomhlaza ohlala kwindawo ethile, ngenxa yokusebenza kwayo ekujoliseni ngokukhethekileyo iiseli ze-tumor.

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2-Azabicyclo[2.2.1]hept-5-en-3-enye CAS:49805-30-3

I-2-Azabicyclo[2.2.1]hept-5-en-3-one yi-bicyclic organic compound ebonakaliswa yi-atom ye-nitrogen ngaphakathi kwesakhiwo sayo seringi kunye neqela elisebenzayo le-ketone. Ngefomula yemolekyuli i-C₇H₉NO, le compound ikwiklasi yee-azabicyclic compounds ezifumene umdla kwi-organic synthesis kunye ne-medical chemistry. Isakhiwo sayo esahlukileyo sinikezela ngeempawu zeekhemikhali ezinomdla, nto leyo eyenza ukuba ibe yindawo ephakathi exabisekileyo ekuhlanganisweni kwee-molecules ezahlukeneyo ze-bioactive. Uphando malunga nokusetyenziswa kwayo okunokwenzeka lubandakanya amayeza kunye neekhemikhali zezolimo, apho isebenza njengomzekelo wokuphuhlisa iikhompawundi ezinokubaluleka konyango.

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