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I-Biscyanatophenylpropane CAS:1156-51-0
I-Biscyanatophenylpropane yikhemikhali equlathe amaqela amabini e-cyano (–C≡N) anamathele kumqolo we-phenylpropane. Ngefomula yemolekyuli i-C₁₄H₁₃N₂, imele udidi lweekhompawundi ezinezicelo ezinokubakho kwi-organic synthesis nakwisayensi yezinto eziphathekayo. Ubukho bamaqela e-cyano bunegalelo kwi-reactivity yayo, okuvumela utshintsho olwahlukeneyo olunokukhokelela kuphuhliso lwezinto ezintsha okanye amayeza. Ulwakhiwo olukhethekileyo lwale khompawundi luyenza ibe yinto enomdla yophando malunga neempawu zayo zeekhemikhali kunye nokusetyenziswa okunokwenzeka kwizicelo eziphambili ezifana neepolymers, ii-agrochemicals, okanye ii-intermediates zamayeza.
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I-Chlorosulfonyl isocyanate CAS:1189-71-5
I-Chlorosulfonyl isocyanate (CSI) yikhemikhali esetyenziswa ngeendlela ezahlukeneyo enefomyula i-ClSO2NCO. Isetyenziswa kakhulu njengesixhobo esiphakathi ekuhlanganiseni iikhompawundi ezahlukeneyo ze-organic, ngakumbi kwimveliso ye-sulfonamides kunye nezinye iiarhente zamayeza. Amaqela asebenzayo e-CSI ahlukile ayivumela ukuba ithathe inxaxheba kwiimpendulo ezahlukeneyo zeekhemikhali, nto leyo eyenza ibe luncedo kwisayensi yezinto kunye neekhemikhali zezolimo. Ngaphezu koko, ukusebenza kwayo kunye nee-amines kunye nee-alcohols kwenza ukuba kuvele izinto eziphuma kwi-sulfamoyl, ezisetyenziswa kwikhemistri yamayeza. Ngenxa yeengozi zayo, kubandakanya ubuthi kunye nokubola, ukuphatha i-chlorosulfonyl isocyanate kufuna amanyathelo okhuseleko angqongqo.
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I-Ammonium benzoate CAS:1863-63-4
I-Ammonium benzoate yityuwa emhlophe ekristale eyenziwe yi-reaction ye-benzoic acid kunye ne-ammonium hydroxide. Isetyenziswa kakhulu kwiindlela ezahlukeneyo, kuquka nesigcini sokutya, i-flavouring agent, nakwi-pharmaceutical formulations. Kwishishini lokutya, i-ammonium benzoate isebenza kakhulu njengesigcini ngenxa yeempawu zayo zokulwa ne-antimicrobial, ithintela ukukhula kwesikhunta kunye neebhaktheriya ekutyeni okune-asidi. Ukongeza, inezicelo kwimveliso yamayeza athile kunye nezinto zokuthambisa. Ukhuseleko lwayo ekusetyenzisweni lumiselwe ziigunya ezilawulayo, nangona kufuneka isetyenziswe ngaphakathi kwemida ecetyiswayo.
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I-1,3,2-dioxathiolane 2,2-dioxide CAS:1072-53-3
I-1,3,2-Dioxathiolane 2,2-dioxide, eyaziwa ngokuba yi-dioxathiolane S-oxide, yi-sulfur-containing heterocyclic compound ene-molecular formula C3H6O3S. Le compound inesakhiwo se-dioxathiolane ring, esibonakaliswa yindlela yayo eyahlukileyo yokwenza ii-athomu ze-sulfur kunye ne-oxygen. Isetyenziswa kakhulu kwi-organic synthesis kunye ne-reagent kwiimpendulo ezahlukeneyo zeekhemikhali. Ngenxa yokubakho kwe-sulfur kunye ne-oxygen, ibonisa i-reactivity eyahlukileyo engasetyenziswa ekwakhiweni kwee-molecules ze-organic ezintsonkothileyo. Uphando malunga nokusetyenziswa kwayo lubandakanya amayeza, ii-agrochemicals, kunye nesayensi yezinto, lugxininisa ukuguquguquka kwayo kunye nokubaluleka kwayo kwi-synthetic chemistry.
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I-3-Hydroxyphenylphosphinyl-propanoic acid CAS:14657-64-8
I-3-Hydroxyphenylphosphinyl-propanoic acid yi-organophosphorus compound ebonakaliswa liqela le-phosphinyl elinamathele kwi-propanoic acid moiety kunye ne-hydroxyl-substituted phenyl ring. Ngefomula ye-molecular C₉H₁₁O₄P, le compound ibonisa iipropati zeekhemikhali ezikhethekileyo ezinokuthi zisebenzise usetyenziso olwahlukeneyo kwi-organic synthesis kunye ne-medicine chemistry. Ukubakho kwe-phenolic hydroxyl kunye neqela elisebenzayo le-phosphinyl kubonisa umsebenzi onokubakho webhayoloji, okwenza ukuba ibe ngumviwa wophando olongezelelweyo malunga nokusetyenziswa kwayo kwezonyango. Ulwakhiwo lwayo lubonelela ngokuguquguquka kotshintsho olujolise ekuphuculeni umsebenzi okanye ukucaciswa kuyilo lwamayeza.
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i-vidarabine CAS:5536-17-4
I-Vidarabine, ekwaziwa ngokuba yi-9-β-D-arabinofuranosyladenine (ara-A), yi-synthetic nucleoside analog ye-adenosine. Ekuqaleni yaphuhliswa njenge-antiviral agent, yayisetyenziswa kakhulu ukunyanga usulelo lwentsholongwane, ngakumbi olo lubangelwa yi-herpes simplex virus (HSV) kunye ne-varicella-zoster virus (VZV). I-Vidarabine ithintela ukuphindaphinda kwentsholongwane ngokuphazamisa ukwenziwa kwe-DNA yentsholongwane kunye ne-RNA, okwenza ukuba isebenze kakuhle ekulawuleni usulelo lwe-herpes olunzima. Ulwakhiwo lwayo olwahlukileyo luvumela ukuba ifakwe kwi-nucleic acids, ngaloo ndlela iphazamisa iinkqubo eziqhelekileyo zeseli. Nangona ingasetyenziswa rhoqo namhlanje ngenxa yokuvela kwamayeza amatsha e-antiviral, i-vidarabine isabalulekile kuphando lwe-virology.
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i-uracil-1-beta-D-arabinofuranoside CAS:3083-77-0
I-Uracil-1-beta-D-arabinofuranoside, eyaziwa ngokuba yi-ara-U, yi-nucleoside analog ephuma kwi-uracil ene-arabinofuranosyl sugar moiety. Olu tshintsho luphucula uzinzo lwayo kunye nokusebenza kwayo xa kuthelekiswa ne-uridine yendalo. I-Ara-U ifundwe ngenxa yeempawu zayo ezinokubakho zokulwa ne-antiviral, ngakumbi ngokuchasene neentsholongwane ze-RNA. Isebenza ngokuthintela ukuphindaphinda kwentsholongwane ngeendlela ezifana nezo zezinye ii-nucleoside analogs, nto leyo eyenza ukuba ibe ngumviwa wokusetyenziswa konyango ekunyangeni usulelo lwentsholongwane. Iimpawu ezizodwa zesakhiwo se-uracil-1-beta-D-arabinofuranoside zivumela ukusebenzisana ne-viral polymerases, nto leyo egxininisa ukubaluleka kwayo kuphando lwezonyango kunye nophuhliso lwamayeza.
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i-cytosine-1-beta-D-arabinofuranoside CAS:147-94-4
I-Cytosine-1-beta-D-arabinofuranoside, eyaziwa ngokuba yi-ara-C okanye i-cytarabine, yi-nucleoside analog ye-cytosine. Ineswekile ye-arabinofuranosyl, ephucula uzinzo lwayo kunye nokusebenza kwayo kwiinkqubo zebhayoloji. I-Ara-C isetyenziswa kakhulu kunyango lweentlobo ngeentlobo ze-malignancies, ingakumbi umhlaza we-hematological ofana ne-acute myeloid leukemia (AML) kunye ne-non-Hodgkin lymphoma. Indlela esebenza ngayo ibandakanya ukufakwa kwi-DNA, ekhokelela ekuthintelweni kokwenziwa kwe-DNA kwaye ekugqibeleni ibangele i-apoptosis kwiiseli ezahlulahlula ngokukhawuleza. Ngenxa yokusebenza kwayo ngokuchasene nomhlaza, i-cytarabine ihlala ingundoqo kwiindlela zonyango lwe-chemotherapy.
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I-Cyclocytidine hydrochloride CAS:10212-25-6
I-Cyclocytidine hydrochloride yi-cyclic nucleoside analog ephuma kwi-cytidine, enesakhiwo esikhethekileyo se-bicyclic esinceda sizinze kwaye sisebenze kakuhle. Isetyenziswa kakhulu kuphando lwamayeza kunye nophuhliso lwezicelo zayo zonyango, ngakumbi kunyango lwe-antiviral kunye nonyango lomhlaza. I-Cyclocytidine inokuguqula imetabolism ye-nucleic acid kwaye ichaphazele iindlela zeseli, iyenze ibe yikhompawundi exabisekileyo yokufunda ukusebenzisana kweemolekyuli ngaphakathi kweeseli. Iimpawu zayo zeekhemikhali zivumela abaphandi ukuba baphonononge iindlela ezintsha zoyilo kunye nokuhanjiswa kwamayeza, inika iindlela ezithembisayo zonyango lwezifo ezinxulumene nomsebenzi ongaqhelekanga we-nucleic acid.
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I-Adenosine Cyclophosphate CAS:60-92-4
I-Adenosine cyclophosphate, edla ngokubizwa ngokuba yi-cyclic adenosine monophosphate (cAMP), sisithunywa sesibini esibalulekileyo kwiindlela zokubonisa iiseli. Yenziwa kwi-ATP ngesenzo se-adenylate cyclase kwaye idlala indima ebalulekileyo ekulawuleni iimpendulo ezahlukeneyo zomzimba emzimbeni. I-cAMP isebenza ngokuvuselela i-protein kinase A (PKA) kunye nezinye ii-cascade zokubonisa, ezikhokelela kwiziphumo ezahlukeneyo zebhayoloji, kubandakanya ukulawulwa kwemetabolism, ukubonakaliswa kwezakhi zofuzo, kunye nokwanda kweeseli. Ukubaluleka kwayo kugubungela iinkqubo ezininzi, kubandakanya iinkqubo ze-nervous kunye ne-endocrine, okwenza i-cAMP ibe ngumdlali ophambili ekugcineni i-homeostasis yeseli kunye nokuphendula kwi-stimuli zangaphandle.
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I-Adenosine 5′-monophosphate CAS:61-19-8
I-Adenosine 5′-monophosphate (AMP) yi-nucleotide edlala indima ebalulekileyo kwi-metabolism yeseli kunye nokudluliselwa kwamandla. Iqulunqwe yisiseko se-adenine, iswekile ye-ribose, kunye neqela elinye le-phosphate, i-AMP ibandakanyeka kwiinkqubo ezahlukeneyo ze-biochemical, kubandakanya ukwenziwa kwe-adenosine triphosphate (ATP) kunye ne-cyclic adenosine monophosphate (cAMP). Njengemolekyuli yokubonisa, i-AMP ilawula iindlela ze-metabolic kwaye isebenza njengomanduleli obalulekileyo kwi-biosynthesis ye-nucleotide. Amanqanaba ayo ngaphakathi kweeseli abonelela ngolwazi olubalulekileyo malunga nesimo samandla eseli, okwenza kube yimfuneko ekugcineni i-homeostasis kunye nokuxhasa imisebenzi ye-physiological kwizinto eziphilayo.
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N(2),9-Diacetylguanine CAS:3056-33-5
I-N(2),9-I-Diacetylguanine yi-synthetic derivative ye-guanine, ephawulekayo ngokongeza amaqela e-acetyl kwiindawo ze-nitrogen 2 kunye ne-9. Olu tshintsho lutshintsha iipropati zeekhemikhali kunye nemisebenzi yebhayoloji ye-guanine, luphucula ukunyibilika kwayo kunye nokusebenza kwayo. I-N(2),9-I-Diacetylguanine isebenza njengebhloko ebalulekileyo yokwakha kwi-nucleic acid chemistry, idlala indima ebalulekileyo kuphando olunxulumene nezakhiwo ze-DNA kunye ne-RNA. Iimpawu zayo ezahlukeneyo zenza ukuba ibe luncedo ekuphuhliseni iiprobe ezintsha kunye neearhente zonyango, okuvumela izazinzulu ukuba ziphande iindlela zeseli kunye nokulawulwa kwezakhi zofuzo ngempumelelo.
