I-CHAPS (3--[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate) sisicoci esisetyenziswa ngokuqhelekileyo kwi-biochemistry kunye ne-molecular biology.Sisicoci se-zwitterionic, okuthetha ukuba sineqela elichasa kakuhle nelibi.
I-CHAPS yaziwa ngokukwazi ukunyibilikisa kunye nokuzinzisa iiproteni ze-membrane, iyenza ibe luncedo kwiinkqubo ezahlukeneyo ezinje ngokutsalwa kweprotein, ukucocwa, kunye nokulinganisa iimpawu.Iphazamisa ukusebenzisana kwe-lipid-protein, ivumela iiprotheni ze-membrane ukuba zikhutshwe kwilizwe labo lokuzalwa.
Ngokungafaniyo nezinye izicoci, i-CHAPS ithambile kwaye ayidibanisi iiprotheyini ezininzi, iyenza ibe lolona khetho lubalaseleyo lokugcina ulwakhiwo lweprotheyini kunye nokusebenza ngexesha lovavanyo.Inokunceda nokuthintela ukudityaniswa kweeprotheyini.
I-CHAPS iqhele ukusetyenziswa kubuchule obufana ne-SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis), ugxininiso lwe-isoelectric, kunye ne-Western blotting.Ikwasetyenziswa rhoqo kwizifundo ezibandakanya i-enzymes ebotshwe kwi-membrane, ukuhanjiswa komqondiso, kunye nokusebenzisana kweprotein-lipid.