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I-Candesartan CAS: 139481-59-7 uMboneleli woMvelisi
I-Candesartan ngumchasi we-angiotensin II receptor I (AT1), i-IC50s=1.12 kunye ne-2.86 nM ye-bovine adrenal cortex kunye ne-aorta yomvundla ngokulandelelana.Inqanda ngokukhethayo i-angiotensin II-i-induced contraction ye-rabbit aortic strips ingenayo impembelelo kwi-contraction ye-nopinephrine , i-KCl, i-serotonin, i-PGF2αokanye i-endothelin.
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Candesartana Cilexetila CAS:145040-37-5
I-Candesartan Celexetil yi-ester analog ye-angiotensin II antagonist Candesartan (sc-217825).I-Antagonism yale receptor ikhusela ukubopha i-angiotensin II, i-vasoconstrictor enamandla.Oku kunesiphumo esipheleleyo se-vasodilation kunye nokunyuka kwevolumu yegazi le-capillary.I-Candesartan Celexetil Ester yi-inhibitor ye-AT1.
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I-Bupropion CAS: 34911-55-2 uMboneleli woMvelisi
I-Bupropion yiketone enuka kamnandi eyipropiophenone ethwele iqela le-tert-butylamino kwindawo yesi-2 kunye ne-chloro ebambeleyo kwindawo yesi-3 kwiringi yephenyl.Inendima njenge-antidepressant, ungcoliseko lokusingqongileyo kunye ne-xenobiotic.Yikhompawundi yesibini ye-amino, ilungu le-monochlorobenzenes kunye ne-ketone enuka kamnandi.
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I-Bezafibrate CAS: 41859-67-0 uMboneleli woMvelisi
I-Bezafibrate i-amide ye-monocarboxylic acid efunyenwe yi-condensation esemthethweni yeqela le-carboxy ye-4-chlorobenzoic acid kunye neqela le-amino le-2--[4- (2-aminoethyl) phenoxy] -2-methylpropanoic acid.I-Benafibrate isetyenziselwa unyango lwe-hyperlipidemia.Inendima njenge-xenobiotic, ungcoliseko lokusingqongileyo, i-geroprotector kunye neyeza elichasayo.Yi-asidi ye-monocarboxylic, i-ether enevumba elimnandi, ilungu le-monochlorobenzenes kunye ne-monocarboxylic acid amide.Isebenza ngokunxulumene nepropionic acid.
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I-Fucoxanthin CAS: 3351-86-8 uMboneleli woMvelisi
I-Fucoxanthin yenye i-xanthophyll ebalulekileyo.Ifumaneka ngokubanzi kwi-heterokontophyta, efana ne-algae emdaka kunye ne-oceanic microalgae, kwaye kukholelwa ukuba yeyesibini kwi-carotenoid eninzi emhlabeni emva kwe-β-carotene.Kutshanje, izifundo malunga nokusebenza kwe-fucoxanthin ziye zaqhutywa ngokwandayo, kwaye i-fucoxanthin ibonakaliswe ukuba inemisebenzi eyahlukeneyo yomzimba eluncedo.
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I-Sitagliptin Phosphate CAS: 654671-78-0 uMboneleli womvelisi
I-Sitagliptin Phosphateyinoveli yokuqala ye-dipeptidyl peptidase IV inhibitor esuka kwi-Merck yonyango lwe-2 yeswekile ngaphandle kokufumana ubunzima kunye nezehlo ze-hypoglycemia zazifana ne-placebo.I-Sitagliptin isebenza ngokuphucula inkqubo ye-incretin yomzimba, enceda ukulawula i-glucose ngokuchaphazela iiseli ze-β kunye ne-α kwi-pancreas.
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I-Aspartate Calcium CAS: 10389-09-0 uMboneleli woMvelisi
I-Aspartate Calciumyenye yezona zimbiwa zininzi emzimbeni kwaye ziyinxalenye ebalulekileyo ebomini bethu.Ngaphandle kwayo, abantu bebengenakukwazi ukugcina amathambo namazinyo omelele.Malunga ne-99% ye-calcium emzimbeni ifakwe kwezi ndawo zimbini.Ukongeza, i-calcium inceda intliziyo, imithambo-luvo, izihlunu kunye nezinye iinkqubo zomzimba zisebenze ngokufanelekileyo.Inokwakheka kweekhemikhali ezizinzileyo, ukunyibilika kakuhle kwamanzi kunye nezinga eliphezulu lokufunxa.Yeyona sizukulwana samva nje se-calcium yesondlo sokuqinisa.
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I-L-Carnitine L-Tartrate CAS: 36687-82-8 uMboneleli woMvelisi
I-L-carnitine yinto ephuma ngokwemvelo ye-amino acid esetyenziswa njengesongezelelo sokulahlekelwa kwesisindo.I-L-carnitine-L-tartrate (LCLT) ityuwa ye-L-carnitine kunye ne-tartaric acid.I-LCLT inemisebenzi enokubakho ye-chemoprotective kunye ne-antioxidant.
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I-Dipyridamol CAS: 58-32-2 uMboneleli woMvelisi
I-Dipyridamol yi-vasodilator esebenza ixesha elide.I-vasodilatingaction yayo ikhetha kwi-coronary system;iboniswa kunyango lwexesha elide lwe-angina pectoris engapheliyo.Iziyobisi ziphinda zithintele i-adenosine deaminase kwi-erythrocytes kwaye iphazamise ukufunyanwa kwe-vasodilator adenosineby erythrocytes.Ezi zenzo zenza impembelelo yeprostacyclin (PGI2), esebenza njenge-inhibitor kwiplateletaggregation.
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I-Losartan Potassium CAS:124750-99-8 uMboneleli woMvelisi
I-Losartan Potassium yityuwa ye-potassium ye-losartan kunye nomsebenzi we-antihypertensive, esetyenziswa kakhulu kunyango lwe-high blood pressure (hypertension) kunye ne-nephropathy yesifo seswekile.Isebenza ngokuphumza imithambo yegazi ukuze igazi likwazi ukuhamba lula.Ikwasebenza ekuncedeni ukukhusela izintso kumonakalo obangelwa sisifo seswekile kunye nokunciphisa umngcipheko we-stroke kwizigulana ezinoxinzelelo lwegazi kunye nokwandiswa kwe-myocardial.
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I-Pregabalin CAS: 148553-50-8 uMboneleli woMvelisi
I-Pregalin ibonakaliswe yiprofayili yokuziphatha kakuhle.Le AED ayibonakali ineziphumo ezibi kwimo yeemvakalelo okanye kwindlela yokuziphatha kwizigulana ezixhuzulayo, nangona ukudakumba kuye kwaxelwa kwezinye izigulana (iziphumo ezixhomekeke kwidosi yobunzulu obuphakathi ukuya kobuphakathi).Ukuxhatshazwa okunokwenzeka okanye ukusetyenziswa kakubi kwe-pregabalin kuye kwaxelwa, kunye neempembelelo malunga nokuxhomekeka kunye nokuhoxiswa.I-pregabalin ikwanxulunyaniswa neziphumo ezibi zokuqonda ezilinganiselweyo, ikakhulu ezinxulumene ne-sedation, ukunciphisa ukuvuswa, ukunciphisa ingqalelo kunye nokugxila (iziphumo ezixhomekeke kwidosi yokuqina okuphakathi ukuya kophakathi).
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I-Citrulline CAS: 372-75-8 uMboneleli woMvelisi
ICitrulline yiL-enantiomer yecitrulline.Inendima njenge-EC 1.14.13.39 (nitric oxide synthase) inhibitor, i-agent ekhuselayo, i-nutraceutical, i-micronutrient, i-metabolite yabantu, i-Escherichia coli metabolite, i-Saccharomyces cerevisiae metabolite kunye ne-metabolite ye-mouse.Yi-enantiomer ye-D-citrulline.Yi-tautomer ye-L-citrulline zwitterion.
