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I-Rosuvastatin Calcium CAS: 147098-20-2 uMboneleli woMvelisi
I-Rosuvastatin calcium yi-inhibitor ekhuphisanayo ye-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, i-enzyme eyenza ukuguqulwa kwe-HMG-CoA kwi-mevalonic acid, inqanaba lokunciphisa izinga kwi-cholesterol biosynthesis.I-Rosuvastatin calcium i-antilipemic kwaye isetyenziselwa ukunciphisa amanqanaba e-cholesterol e-plasma kunye nokukhusela isifo senhliziyo.
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I-Glycine CAS: 56-40-6 uMboneleli woMvelisi
I-Glycine yesona sakhiwo silula kumalungu angama-20 ochungechunge lwe-amino acid, eyaziwa ngokuba yi-amino acetate.Yi-amino acid engabalulekanga kumzimba womntu kwaye iqulethe zombini i-acidic kunye neqela elisisiseko elisebenzayo ngaphakathi kwe-molecule yayo.Ibonisa njenge-electrolyte eyomeleleyo isisombululo esinamanzi, kwaye ine-solubility enkulu kwi-solvents eqinile ye-polar kodwa iphantse inganyibiliki kwi-solvents non-polar.Ngaphezu koko, inendawo yokunyibilika ephezulu kunye nenqanaba lokubila.Ukulungelelaniswa kwe-pH yesisombululo samanzi kunokwenza i-glycine ibonise iifom ezahlukeneyo ze-molecular.
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I-L-Arginine Pyroglutamate CAS: 56265-06-6 uMboneleli woMvelisi
I-L-Arginine pyroglutamate, eyaziwa ngokuba yi-pirglutargine kunye ne-arginine pidolate, yityuwa ye-L-arginine ye-pyroglutamic acid.I-Arginine pyroglutamate yindlela yokuhanjiswa kwe-arginine.I-L-Arginine-L-pyroglutamate isetyenziswa ngokuqhelekileyo njengama-pharmaceutical intermediates.
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I-Dapagliflozin Propanediol CAS: 461432-26-8
I-Dapagliflozin Propanediol, i-sodium glucose cotransporter 2 inhibitor, luhlobo olutsha lweziyobisi ezichasene nesifo seswekile;Ingasetyenziswa njengokhetho olubalulekileyo kunyango lweziyobisi lwesifo sikashukela, kwaye lunokusetyenziswa njengesondlo esincedisayo kunye nokuzivocavoca ukuphucula ulawulo lweswekile yegazi kubantu abadala abane-2 yeswekile.
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I-Leflunomide CAS: 75706-12-6 uMboneleli woMvelisi
I-Leflunomide sisiyobisi se-antirheumatic esifumaneka ngomlomo kwaye yasungulwa njenge-Arava e-US kunyango lwe-rheumatoid arthritis (RA);liyeza lokuqala kunye nekuphela kweyeza eliya kuboniswa ukuba licothise umonakalo odibeneyo wesakhiwo se-RA, ngoko ke ukujongana nesidingo sonyango esingafezekiyo.I-Leflunomide yi-pro-drug ekhawulezayo kwaye iphantse isetyenziswe ngokupheleleyo kwi-metabolized (isiqingatha sobomi,
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Tofacitinib CAS:477600-75-2 uMboneleli woMvelisi
I-Tofacitinib yi-molecule yokuqala encinci ye-kinase inhibitor evunyiweyo kunyango lwe-RA.I-Tofacitinib iyi-inhibitor ye-subtypes ezine ze-Janus kinase (JAK): i-JAK1, i-JAK2, i-JAK3, kunye ne-Tyk2.Izenzo ze-Tofacitinib ngokuvimbela i-phosphorylation kunye nokusebenza kwe-transducers yesignali kunye ne-activators of transcription (STATs), ngaloo ndlela icinezela abalamli abavuthayo. kwizicubu ezidibeneyo.
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I-Aspartic Acid CAS: 56-84-8 uMboneleli woMvelisi
Aspartic Acidisetyenziswa njengesongezelelo sokutya, inokudityaniswa neeminerali ukwenza iikhompawundi ezifana ne-potassium aspartate, i-copper aspartate, i-manganese aspartate, i-magnesium aspartate, i-zinc aspartate kunye nokunye.Ukonyusa ukufunxwa, kunye nokusetyenziswa okunokwenzeka, kwezi zimbiwa ngokongezwa kweaspartate kubangela izibonelelo ezithile zempilo.Iimbaleki ezininzi zisebenzisa izongezelelo zeminerali ezisekwe kwi-L-aspartic acid ngomlomo ukukhulisa amandla abo okusebenza.I-Aspartic acid kunye ne-glutamic acid idlala indima ebalulekileyo njenge-asidi ngokubanzi kumaziko asebenzayo e-enzyme, kunye nokugcina i-solubility kunye ne-ionic character of proteins.
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I-Cetilistat CAS: 282526-98-1 uMboneleli woMvelisi
I-Cetilistat luhlobo olutsha lwe-pancrelipase inhibitor kunyango lokutyeba kakhulu kwi-diabetic kunye ne-non-diabetic, i-gastrointestinal lipase inhibitor esebenza ixesha elide, edlala umphumo wonyango ngokwenza i-covalent bond kunye ne-serine site esebenzayo ye-gastric lipase. kunye ne-pancreatic lipase esiswini kunye namathumbu amancinci ukuze angasebenzi i-enzyme.I-enzymes ye-Living Chemicalbook ayikwazi ukwenza i-hydrolyze amanqatha ekutyeni, ngakumbi i-triglycerides ibe yi-acids efunxayo yasimahla kunye ne-monoacylglycerols.I-triglycerides engaxutywanga ayinakuthatyathwa ngumzimba, ngaloo ndlela inciphisa i-caloric intake kunye nokulawula ubunzima.
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I-Paroxetine HCL CAS: 78246-49-8 uMboneleli woMvelisi
I-Paroxetine hydrochloride yityuwa ye-hydrochloride ye-paroxetine.Lichiza lokuthomalalisa uxinzelelo.Inendima njenge-antidepressant, i-anxiolytic drug, i-hepatotoxic agent, i-P450 inhibitor kunye ne-serotonin uptake inhibitor.Iqulethe i-paroxetinium (1+).
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I-Famotidine CAS: 76824-35-6
I-Famotidine ngumchasi we-histamine H2-receptor, okhuthaza ukuphiliswa kwe-erosive esophagitis, izilonda zesisu kunye ne-duodenal kuba inqanda ukukhutshwa kwe-asidi yesisu ebantwini.It isetyenziselwa unyango kunye nokuthintela izilonda ezenzeka esiswini kunye namathumbu.Iyakwazi ukunyanga izifo ezifana neZollinger-Ellison syndrome apho isisu siqokelela ubuninzi beeasidi.Ngaphezu koko, isetyenziswe ngexesha lokunyanga isifo se-reflux ye-gastroesophageal (GERD) kunye neemeko ze-pathological hypersecretory.
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I-Rivaroxaban CAS: 366789-02-8 uMboneleli woMvelisi
I-Rivaroxaban i-agent ye-antithrombotic inoveli.Yinoveli, ngomlomo, inhibitor ekhethiweyo ethe ngqo ye-factor Xa ephuhliswe yi-Bayer Healthcare.Ivunyiwe yi-EMEA kunye ne-FDA yokuthintela i-thromboembolism eyingozi kwizigulane zabantu abadala emva kokutshintshwa kwe-hip epheleleyo okanye utyando olupheleleyo lokuguqa.
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I-Glutamine CAS: 56-85-9 uMboneleli woMvelisi
I-Glutamine yi-alpha-amino acid enye ye-20 amino acids equkethe iiprotheni.I-L-glutamine yi-amino acids engabalulekanga kwaye ikwayeyona ininzi kakhulu kwimizimba yabantu.Ibandakanyeka kwiinkqubo ezininzi zebhayoloji ezibalulekileyo.Ngokomzekelo, yibhloko yokwakha iprotheni synthesis njengenye i-amino acid ephambili;isetyenziswe kwi-biosynthesis ye-urea kunye ne-purines ye-nucleic acid synthesis;yi-substrate ye-biosynthesis ye-neurotransmitters;ikwayimithombo ebalulekileyo yokuveliswa kwamandla eselula.
