I-Fmoc-D-Asn-OH CAS:108321-39-7

I-Fmoc-D-Asn-OH ngumdlali ophambili ekuhlanganisweni kwe-peptide, ngakumbi kwindibano elawulwayo yee-peptides eziqulathe i-D-enantiomer ye-asparagine. Iqela elikhuselayo le-Fmoc likhusela iqela le-amino, liqinisekisa iimpendulo ezikhethiweyo ngexesha lokudibanisa i-peptide. Le khompawundi isetyenziswa kakhulu ekuhlanganisweni kwee-peptides kwizifundo zebhayoloji, uphuhliso lwamayeza, kunye noyilo lwee-peptides ezisebenzayo ezinee-stereochemical configurations ezithile. Ukuguquguquka kwe-Fmoc-D-Asn-OH kufikelela kwisicelo sayo ekwakheni ii-peptides ezinee-D-asparagine residues, negalelo ekuphuhlisweni kwee-peptides ezinezakhiwo kunye nemisebenzi eyenzelwe wena. Abaphandi basebenzisa ukuhambelana kwayo neendlela eziqhelekileyo zokwenziwa kwe-peptide, beyisebenzisa kwiindlela ezahlukeneyo zokwenziwa kwe-peptide. Ukuzinza kwayo kunye nokulula kokuguqulwa kwayo kwenza kube lukhetho olukhethwayo lokuvelisa ii-peptides ezinotshintsho oluchanekileyo, ngakumbi ezo zibandakanya ii-D-amino acids. Ngaphezu koko, i-Fmoc-D-Asn-OH ifumana uncedo ekuhlanganisweni kwee-peptides zezinto eziphilayo, uphando lwe-proteomics, kunye nophando lweenkqubo zeseli, apho ukufakwa kwee-D-amino acids kunokunika iipropati ezikhethekileyo. Ukususwa kokhuseleko olulawulwayo lweqela le-Fmoc kuvumela ukufakwa kwe-D-asparagine ngokweqhinga kulandelelwano lwe-peptide. Ngamafutshane, i-Fmoc-D-Asn-OH imi njengesixhobo esiguquguqukayo nesingenamsebenzi kwi-peptide chemistry, iqhubela phambili uphando kunye nokusetyenziswa kwiindawo ezahlukeneyo zesayensi kugxilwe kwi-D-amino acid-containing peptides.