1,4-Dithioerythritol (DTE) CAS:6892-68-8

I-Agent yokunciphisa: i-DTE isetyenziswa ngokuqhelekileyo ukuphula iibhondi ze-disulfide kwiimolekyuli.Inokunciphisa i-disulfide-containing compounds kwifom ye-thiol, evumela abaphandi ukuba bafunde imeko encitshisiweyo yeeprotheni, i-peptides, kunye nezinye i-biomolecules.Oku kubaluleke kakhulu ekucoceni iiprotheyini kunye nokulungiswa kwesampulu, njengoko inceda ukuthintela ukuhlanganiswa kweeprotheni kunye nokugcina uzinzo lweprotheni.

I-Protein Denaturation: I-DTE ingasetyenziselwa ukuguqula iiproteni ngokuphazamisa ubume bazo obuphezulu.Oku kuluncedo kwizifundo zeprotheyini apho ukutyhilwa kunye nokuphinda kuphindwe kufunwa, njengokumisela iprotheyini yokusonga i-kinetics okanye ukuphanda iprotein-protein interactions.

I-Antioxidant: I-DTE ineempawu ze-antioxidant kwaye inokukhupha ii-radicals zamahhala kunye neentlobo ze-oksijini ezisebenzayo (ROS).Inceda ukukhusela iiseli kunye ne-biomolecules kumonakalo we-oxidative obangelwa yi-ROS.I-DTE ingasetyenziswa kuvavanyo lwenkcubeko yeeseli ukufunda iziphumo zoxinzelelo lwe-oxidative kwiiseli kunye nokuvavanya umsebenzi we-antioxidant.

I-Enzyme Inhibition Studies: I-DTE isoloko isetyenziswa njengolawulo olubi okanye inhibitor kwizifundo zokunqanda i-enzyme.Ngokuthintela ngokungenakuguquleka indawo esebenzayo ye-enzyme, inceda abaphandi ukuba bamisele into ethile kunye nendlela yokuthintela i-enzyme ngamanye amakhompawundi.

I-Chemical synthesis: I-DTE ingasetyenziswa kwi-chemical synthesis njenge-arhente yokunciphisa ukuguqulwa kweekhompawundi ze-carbonyl kwii-alcohols ezihambelanayo.Iluncedo ngakumbi kwi-asymmetric synthesis, apho i-stereoelectivity ifunwayo.